6v92
From Proteopedia
(Difference between revisions)
m (Protected "6v92" [edit=sysop:move=sysop]) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==RSC-NCP== | |
| + | <SX load='6v92' size='340' side='right' viewer='molstar' caption='[[6v92]], [[Resolution|resolution]] 20.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6v92]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V92 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6V92 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 20Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6v92 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v92 OCA], [https://pdbe.org/6v92 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6v92 RCSB], [https://www.ebi.ac.uk/pdbsum/6v92 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6v92 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RSC3_YEAST RSC3_YEAST] Component of the chromatin structure-remodeling complex (RSC), which is involved in transcription regulation and nucleosome positioning. RSC is responsible for the transfer of a histone octamer from a nucleosome core particle to naked DNA. The reaction requires ATP and involves an activated RSC-nucleosome intermediate. Remodeling reaction also involves DNA translocation, DNA twist and conformational change. As a reconfigurer of centromeric and flanking nucleosomes, RSC complex is required both for proper kinetochore function in chromosome segregation and, via a PKC1-dependent signaling pathway, for organization of the cellular cytoskeleton. This subunit is required for transcription of ribosomal protein genes and genes involved in the integrity of the cell wall, and also for proper metaphase progression. Together with HTL1, LDB7, NPL6, RSC30 components, defines a fungal-specific module within the RSC complex that plays a role in many cellular functions including the maintenance of cell wall integrity.<ref>PMID:10025404</ref> <ref>PMID:10329629</ref> <ref>PMID:11336698</ref> <ref>PMID:12072455</ref> <ref>PMID:12183366</ref> <ref>PMID:12697820</ref> <ref>PMID:16204215</ref> <ref>PMID:8980231</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Actin-related protein 3D structures|Actin-related protein 3D structures]] | |
| - | + | *[[Helicase 3D structures|Helicase 3D structures]] | |
| - | [[Category: | + | *[[Histone 3D structures|Histone 3D structures]] |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </SX> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Greber BJ]] | ||
| + | [[Category: Moore CM]] | ||
| + | [[Category: Nogales E]] | ||
| + | [[Category: Patel AB]] | ||
Current revision
RSC-NCP
| |||||||||
