6mgz

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Current revision (14:42, 13 March 2024) (edit) (undo)
 
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<StructureSection load='6mgz' size='340' side='right'caption='[[6mgz]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='6mgz' size='340' side='right'caption='[[6mgz]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6mgz]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pneumoniae"_(schroeter_1886)_flugge_1886 "bacillus pneumoniae" (schroeter 1886) flugge 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MGZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6MGZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6mgz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6MGZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6MGZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.647&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blaNDM-4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=573 "Bacillus pneumoniae" (Schroeter 1886) Flugge 1886])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6mgz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mgz OCA], [http://pdbe.org/6mgz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6mgz RCSB], [http://www.ebi.ac.uk/pdbsum/6mgz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6mgz ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6mgz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6mgz OCA], [https://pdbe.org/6mgz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6mgz RCSB], [https://www.ebi.ac.uk/pdbsum/6mgz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6mgz ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/BLAN1_KLEPN BLAN1_KLEPN] Confers resistance to many beta-lactam antibiotics, including some carbapenems. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Klebsiella pneumoniae]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Babnigg, G]]
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[[Category: Babnigg G]]
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[[Category: Structural genomic]]
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[[Category: Jedrzejczak R]]
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[[Category: Jedrzejczak, R]]
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[[Category: Joachimiak A]]
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[[Category: Joachimiak, A]]
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[[Category: Kim Y]]
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[[Category: Kim, Y]]
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[[Category: Tesar C]]
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[[Category: Tesar, C]]
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[[Category: Carbapenemase]]
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[[Category: Csgid]]
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[[Category: Hydrolase]]
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[[Category: Metallo beta lactamase]]
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Current revision

Crystal Structure of the New Deli Metallo Beta Lactamase Variant 4 from Klebsiella pneumoniae

PDB ID 6mgz

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