6tda
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Structure of SWI/SNF chromatin remodeler RSC bound to a nucleosome== | |
| + | <StructureSection load='6tda' size='340' side='right'caption='[[6tda]], [[Resolution|resolution]] 15.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6tda]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TDA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TDA FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 15Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tda FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tda OCA], [https://pdbe.org/6tda PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tda RCSB], [https://www.ebi.ac.uk/pdbsum/6tda PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tda ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | ||
| - | + | ==See Also== | |
| - | + | *[[Actin-related protein 3D structures|Actin-related protein 3D structures]] | |
| - | + | *[[Helicase 3D structures|Helicase 3D structures]] | |
| - | [[Category: | + | *[[Histone 3D structures|Histone 3D structures]] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Xenopus laevis]] | ||
| + | [[Category: Cramer P]] | ||
| + | [[Category: Dienemann C]] | ||
| + | [[Category: Stuetzer A]] | ||
| + | [[Category: Tegunov D]] | ||
| + | [[Category: Urlaub H]] | ||
| + | [[Category: Wagner FR]] | ||
| + | [[Category: Wang H]] | ||
Current revision
Structure of SWI/SNF chromatin remodeler RSC bound to a nucleosome
| |||||||||||
