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6vab
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6vab is ON HOLD Authors: Kendall, A.K., Jackson, L.P. Description: Mouse retromer sub-structure: VPS35/VPS35 flat dimer [[Category: Unreleased Stru...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Mouse retromer sub-structure: VPS35/VPS35 flat dimer== | |
| + | <SX load='6vab' size='340' side='right' viewer='molstar' caption='[[6vab]], [[Resolution|resolution]] 4.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6vab]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VAB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VAB FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.9Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vab FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vab OCA], [https://pdbe.org/6vab PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vab RCSB], [https://www.ebi.ac.uk/pdbsum/6vab PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vab ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VPS29_MOUSE VPS29_MOUSE] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro). | ||
| - | + | ==See Also== | |
| - | + | *[[Vacuolar protein sorting-associated protein 3D structures|Vacuolar protein sorting-associated protein 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </SX> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Jackson | + | [[Category: Mus musculus]] |
| + | [[Category: Jackson LP]] | ||
| + | [[Category: Kendall AK]] | ||
Current revision
Mouse retromer sub-structure: VPS35/VPS35 flat dimer
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