5dqq

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:25, 6 March 2024) (edit) (undo)
 
(One intermediate revision not shown.)
Line 3: Line 3:
<StructureSection load='5dqq' size='340' side='right'caption='[[5dqq]], [[Resolution|resolution]] 2.87&Aring;' scene=''>
<StructureSection load='5dqq' size='340' side='right'caption='[[5dqq]], [[Resolution|resolution]] 2.87&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5dqq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DQQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DQQ FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5dqq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DQQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DQQ FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=66R:TRANS-NED+19'>66R</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.872&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TPC1, CCH1, FOU2, At4g03560, F9H3.19, T5L23.5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=66R:TRANS-NED+19'>66R</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dqq OCA], [http://pdbe.org/5dqq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dqq RCSB], [http://www.ebi.ac.uk/pdbsum/5dqq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5dqq ProSAT]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dqq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dqq OCA], [https://pdbe.org/5dqq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dqq RCSB], [https://www.ebi.ac.uk/pdbsum/5dqq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dqq ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/TPC1_ARATH TPC1_ARATH]] Functions as a voltage-gated inward-rectifying Ca(2+) channel (VDCC) across the vacuole membrane. Is one of the essential components of the slow vacuolar (SV) channel. Acts as the major ROS-responsive Ca(2+) channel and is the possible target of Al-dependent inhibition. Involved in the regulation of germination and stomatal movement.<ref>PMID:15464979</ref> <ref>PMID:15772667</ref>
+
[https://www.uniprot.org/uniprot/TPC1_ARATH TPC1_ARATH] Functions as a voltage-gated inward-rectifying Ca(2+) channel (VDCC) across the vacuole membrane. Is one of the essential components of the slow vacuolar (SV) channel. Acts as the major ROS-responsive Ca(2+) channel and is the possible target of Al-dependent inhibition. Involved in the regulation of germination and stomatal movement.<ref>PMID:15464979</ref> <ref>PMID:15772667</ref>
==See Also==
==See Also==
Line 17: Line 17:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Arath]]
+
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Kintzer, A F]]
+
[[Category: Kintzer AF]]
-
[[Category: Stroud, R M]]
+
[[Category: Stroud RM]]
-
[[Category: Asymmetric ion channel]]
+
-
[[Category: C-terminal domain]]
+
-
[[Category: Calcium channel]]
+
-
[[Category: Calcium sensor]]
+
-
[[Category: Ef-hand domain]]
+
-
[[Category: Ion channel]]
+
-
[[Category: Membrane protein]]
+
-
[[Category: N-terminal domain]]
+
-
[[Category: Phosphorylation dependent ion channel]]
+
-
[[Category: Pore gate]]
+
-
[[Category: Selectivity filter]]
+
-
[[Category: Sodium channel]]
+
-
[[Category: Tandem pore-forming domain]]
+
-
[[Category: Transport protein-inhibitor complex]]
+
-
[[Category: Voltage sensor]]
+

Current revision

Structure, inhibition and regulation of two-pore channel TPC1 from Arabidopsis thaliana

PDB ID 5dqq

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools