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1tyq
From Proteopedia
(Difference between revisions)
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<StructureSection load='1tyq' size='340' side='right'caption='[[1tyq]], [[Resolution|resolution]] 2.55Å' scene=''> | <StructureSection load='1tyq' size='340' side='right'caption='[[1tyq]], [[Resolution|resolution]] 2.55Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1tyq]] is a 7 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1tyq]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TYQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TYQ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tyq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tyq OCA], [https://pdbe.org/1tyq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tyq RCSB], [https://www.ebi.ac.uk/pdbsum/1tyq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tyq ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/ARP3_BOVIN ARP3_BOVIN] Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis (By similarity). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</div> | </div> | ||
<div class="pdbe-citations 1tyq" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 1tyq" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Actin-related protein 3D structures|Actin-related protein 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Littlefield | + | [[Category: Littlefield RS]] |
| - | [[Category: Nolen | + | [[Category: Nolen BJ]] |
| - | [[Category: Pollard | + | [[Category: Pollard TD]] |
| - | + | ||
Current revision
Crystal structure of Arp2/3 complex with bound ATP and calcium
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