6vda
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6vda is ON HOLD Authors: Maher, M.J. Description: Metal-bound C-terminal domain of CzcD transporter from Thermotoga maritima [[Category: Unreleased...) |
|||
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Metal-bound C-terminal domain of CzcD transporter from Thermotoga maritima== | |
| + | <StructureSection load='6vda' size='340' side='right'caption='[[6vda]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6vda]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VDA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VDA FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vda FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vda OCA], [https://pdbe.org/6vda PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vda RCSB], [https://www.ebi.ac.uk/pdbsum/6vda PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vda ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q9WZX9_THEMA Q9WZX9_THEMA] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Zinc is a potent antimicrobial component of the innate immune response at the host-pathogen interface. Bacteria subvert or resist host zinc insults by metal efflux pathways that include cation diffusion facilitator (CDF) proteins. The structural and functional examination of this protein class has been limited, with only the structures of the zinc transporter YiiP proteins from E. coli and Shewanella oneidensis described to date. Here, we determine the metal binding properties, solution quaternary structures and three dimensional architectures of the C-terminal domains of the metal transporter CzcD proteins from Cupriavidus metallidurans, Pseudomonas aeruginosa and Thermotoga maritima. We reveal significant diversity in the metal-binding properties and structures of these proteins and discover a potential novel mechanism for metal-promoted dimerization for the Cupriavidus metallidurans and Pseudomonas aeruginosa proteins. | ||
| - | + | Structural and functional characterizations of the C-terminal domains of CzcD proteins.,Udagedara SR, La Porta DM, Spehar C, Purohit G, Hein MJA, Fatmous ME, Casas Garcia GP, Ganio K, McDevitt CA, Maher MJ J Inorg Biochem. 2020 Jul;208:111087. doi: 10.1016/j.jinorgbio.2020.111087. Epub , 2020 Apr 23. PMID:32505855<ref>PMID:32505855</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| - | [[Category: Maher | + | <div class="pdbe-citations 6vda" style="background-color:#fffaf0;"></div> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Thermotoga maritima MSB8]] | ||
| + | [[Category: Maher MJ]] | ||
Current revision
Metal-bound C-terminal domain of CzcD transporter from Thermotoga maritima
| |||||||||||
