6uby

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==Isolated cofilin bound to an actin filament==
==Isolated cofilin bound to an actin filament==
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<StructureSection load='6uby' size='340' side='right'caption='[[6uby]], [[Resolution|resolution]] 7.50&Aring;' scene=''>
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<SX load='6uby' size='340' side='right' viewer='molstar' caption='[[6uby]], [[Resolution|resolution]] 7.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6uby]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UBY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UBY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6uby]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6UBY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6vao|6vao]], [[6vau|6vau]], [[6uc0|6uc0]], [[6uc4|6uc4]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6uby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uby OCA], [http://pdbe.org/6uby PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6uby RCSB], [http://www.ebi.ac.uk/pdbsum/6uby PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6uby ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6uby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uby OCA], [https://pdbe.org/6uby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6uby RCSB], [https://www.ebi.ac.uk/pdbsum/6uby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6uby ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. [[http://www.uniprot.org/uniprot/COF1_HUMAN COF1_HUMAN]] Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization.<ref>PMID:15580268</ref> <ref>PMID:21834987</ref>
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[https://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
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== References ==
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<references/>
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==See Also==
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*[[Actin 3D structures|Actin 3D structures]]
__TOC__
__TOC__
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</StructureSection>
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</SX>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
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[[Category: Bibeau, J P]]
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[[Category: Bibeau JP]]
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[[Category: Cao, W]]
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[[Category: Cao W]]
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[[Category: Cruz, E M.De La]]
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[[Category: De La Cruz EM]]
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[[Category: Huehn, A R]]
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[[Category: Huehn AR]]
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[[Category: Schramm, A C]]
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[[Category: Schramm AC]]
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[[Category: Sindelar, C V]]
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[[Category: Sindelar CV]]
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[[Category: Cytoskeleton]]
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[[Category: Structural protein]]
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Current revision

Isolated cofilin bound to an actin filament

6uby, resolution 7.50Å

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