1tz5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (00:32, 21 November 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
==[pNPY19-23]-hPP bound to DPC Micelles==
==[pNPY19-23]-hPP bound to DPC Micelles==
-
<StructureSection load='1tz5' size='340' side='right'caption='[[1tz5]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+
<StructureSection load='1tz5' size='340' side='right'caption='[[1tz5]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1tz5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZ5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1TZ5 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1tz5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TZ5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TZ5 FirstGlance]. <br>
-
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ljv|1ljv]], [[1f8p|1f8p]], [[1tz4|1tz4]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPY, PNP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tz5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tz5 OCA], [https://pdbe.org/1tz5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tz5 RCSB], [https://www.ebi.ac.uk/pdbsum/1tz5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tz5 ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1tz5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tz5 OCA], [http://pdbe.org/1tz5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1tz5 RCSB], [http://www.ebi.ac.uk/pdbsum/1tz5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1tz5 ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/PAHO_HUMAN PAHO_HUMAN]] Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions. The physiological role for the icosapeptide has not yet been elucidated.
+
[https://www.uniprot.org/uniprot/NPY_PIG NPY_PIG] NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.[https://www.uniprot.org/uniprot/PAHO_HUMAN PAHO_HUMAN] Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions. The physiological role for the icosapeptide has not yet been elucidated.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 16: Line 15:
<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tz/1tz5_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tz/1tz5_consurf.spt"</scriptWhenChecked>
-
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
Line 34: Line 33:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Aguilar, M I]]
+
[[Category: Sus scrofa]]
-
[[Category: Beck-Sickinger, A G]]
+
[[Category: Aguilar MI]]
-
[[Category: Folkers, G]]
+
[[Category: Beck-Sickinger AG]]
-
[[Category: Kamimori, H]]
+
[[Category: Folkers G]]
-
[[Category: Lerch, M]]
+
[[Category: Kamimori H]]
-
[[Category: Zerbe, O]]
+
[[Category: Lerch M]]
-
[[Category: Hormone-growth factor complex]]
+
[[Category: Zerbe O]]
-
[[Category: Npy-pp chimera]]
+

Current revision

[pNPY19-23]-hPP bound to DPC Micelles

PDB ID 1tz5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools