5bo2

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<StructureSection load='5bo2' size='340' side='right'caption='[[5bo2]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='5bo2' size='340' side='right'caption='[[5bo2]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5bo2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycta Mycta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BO2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5bo2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Ra Mycobacterium tuberculosis H37Ra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BO2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7P1:2-[(2-CARBOXYPHENYL)AMINO]-5-(3-PHOSPHONOPROPOXY)BENZOIC+ACID'>7P1</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3qr9|3qr9]], [[4ij1|4ij1]], [[5bo3|5bo3]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7P1:2-[(2-CARBOXYPHENYL)AMINO]-5-(3-PHOSPHONOPROPOXY)BENZOIC+ACID'>7P1</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">trpD, MRA_2208 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=419947 MYCTA])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bo2 OCA], [https://pdbe.org/5bo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bo2 RCSB], [https://www.ebi.ac.uk/pdbsum/5bo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bo2 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Anthranilate_phosphoribosyltransferase Anthranilate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.18 2.4.2.18] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bo2 OCA], [http://pdbe.org/5bo2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bo2 RCSB], [http://www.ebi.ac.uk/pdbsum/5bo2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bo2 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA]] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
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[https://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Anthranilate phosphoribosyltransferase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Mycta]]
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[[Category: Mycobacterium tuberculosis H37Ra]]
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[[Category: Baker, E N]]
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[[Category: Baker EN]]
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[[Category: Evans, G L]]
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[[Category: Evans GL]]
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[[Category: Lott, J S]]
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[[Category: Lott JS]]
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[[Category: Structural genomic]]
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[[Category: Lobenzarit-like analogue]]
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[[Category: Magnesium binding]]
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[[Category: Tbsgc]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

Bianthranilate-like inhibitor with 4-atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)

PDB ID 5bo2

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