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| | <StructureSection load='5tk0' size='340' side='right'caption='[[5tk0]], [[Resolution|resolution]] 1.79Å' scene=''> | | <StructureSection load='5tk0' size='340' side='right'caption='[[5tk0]], [[Resolution|resolution]] 1.79Å' scene=''> |
| | == Structural highlights == | | == Structural highlights == |
| - | <table><tr><td colspan='2'>[[5tk0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TK0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TK0 FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[5tk0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TK0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TK0 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.795Å</td></tr> |
| - | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr> | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tk0 OCA], [http://pdbe.org/5tk0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tk0 RCSB], [http://www.ebi.ac.uk/pdbsum/5tk0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tk0 ProSAT]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tk0 OCA], [https://pdbe.org/5tk0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tk0 RCSB], [https://www.ebi.ac.uk/pdbsum/5tk0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tk0 ProSAT]</span></td></tr> |
| | </table> | | </table> |
| | == Function == | | == Function == |
| - | [[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref> | + | [https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref> |
| | <div style="background-color:#fffaf0;"> | | <div style="background-color:#fffaf0;"> |
| | == Publication Abstract from PubMed == | | == Publication Abstract from PubMed == |
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| | [[Category: Gallus gallus]] | | [[Category: Gallus gallus]] |
| | [[Category: Large Structures]] | | [[Category: Large Structures]] |
| - | [[Category: Lysozyme]]
| + | [[Category: Breadmore MC]] |
| - | [[Category: Breadmore, M C]] | + | [[Category: Bunton G]] |
| - | [[Category: Bunton, G]] | + | [[Category: Kilah NL]] |
| - | [[Category: Kilah, N L]] | + | [[Category: MacDonald N]] |
| - | [[Category: MacDonald, N]] | + | [[Category: Park AY]] |
| - | [[Category: Park, A Y]] | + | |
| - | [[Category: Hydrolase]]
| + | |
| Structural highlights
Function
LYSC_CHICK Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1]
Publication Abstract from PubMed
3D printed micrometer-scale polymer mounts for single crystal analysis have been prepared by photopolymerization using digital light projection stereolithography (DLP-SLA), with a commercially available digital light projection stereolithography printer (US$4000) and 3DM-ABS resin (US$150 per liter). The polymer mounts were prepared in batches of 49 in 1 h 15 min, which allowed for rapid prototyping and testing of new crystal mounting designs, with a resin cost of 0.2 cent US per mount. The suitability of the 3D printed mounts for single crystal crystallography has been demonstrated through their use in Cu Kalpha X-ray diffraction experiments of Rochelle salt (sodium potassium tartrate), the protein lysozyme, and has been employed for routine crystallographic analysis of organic and inorganic materials.
3D Printed Micrometer-Scale Polymer Mounts for Single Crystal Analysis.,Macdonald NP, Bunton GL, Park AY, Breadmore MC, Kilah NL Anal Chem. 2017 Mar 30. doi: 10.1021/acs.analchem.7b00443. PMID:28319372[2]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021
- ↑ Macdonald NP, Bunton GL, Park AY, Breadmore MC, Kilah NL. 3D Printed Micrometer-Scale Polymer Mounts for Single Crystal Analysis. Anal Chem. 2017 Mar 30. doi: 10.1021/acs.analchem.7b00443. PMID:28319372 doi:http://dx.doi.org/10.1021/acs.analchem.7b00443
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