1vmp
From Proteopedia
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==STRUCTURE OF THE ANTI-HIV CHEMOKINE VMIP-II== | ==STRUCTURE OF THE ANTI-HIV CHEMOKINE VMIP-II== | ||
| - | <StructureSection load='1vmp' size='340' side='right'caption='[[1vmp | + | <StructureSection load='1vmp' size='340' side='right'caption='[[1vmp]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1vmp]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1vmp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_gammaherpesvirus_8 Human gammaherpesvirus 8]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VMP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VMP FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 1 model</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vmp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vmp OCA], [https://pdbe.org/1vmp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vmp RCSB], [https://www.ebi.ac.uk/pdbsum/1vmp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vmp ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/VMI2_HHV8P VMI2_HHV8P] Blocks infection by several different human immunodeficiency virus type 1 (HIV-1) strains. This occurs because vMIP-II binds to a wide range of chemokine receptors. May form part of the response to host defenses contributing to virus-induced neoplasia and may have relevance to KSHV and HIV-I interactions. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vm/1vmp_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vm/1vmp_consurf.spt"</scriptWhenChecked> | ||
| - | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Human gammaherpesvirus 8]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Liwang | + | [[Category: Liwang AC]] |
| - | [[Category: Liwang | + | [[Category: Liwang PJ]] |
| - | [[Category: Peiper | + | [[Category: Peiper SC]] |
| - | [[Category: Sun | + | [[Category: Sun Y]] |
| - | [[Category: Wang | + | [[Category: Wang Z-X]] |
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Current revision
STRUCTURE OF THE ANTI-HIV CHEMOKINE VMIP-II
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