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6pb5
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The E. coli class-II CAP-dependent transcription activation complex at the state 1 architecture== |
| + | <StructureSection load='6pb5' size='340' side='right'caption='[[6pb5]], [[Resolution|resolution]] 4.52Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6pb5]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PB5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6PB5 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.52Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6pb5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6pb5 OCA], [https://pdbe.org/6pb5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6pb5 RCSB], [https://www.ebi.ac.uk/pdbsum/6pb5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6pb5 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CRP_ECOLI CRP_ECOLI] This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons. The protein induces a severe bend in the DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP.<ref>PMID:2982847</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[RNA polymerase 3D structures|RNA polymerase 3D structures]] | |
| - | + | *[[Sigma factor 3D structures|Sigma factor 3D structures]] | |
| - | [[Category: | + | == References == |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Liu B]] | ||
| + | [[Category: Shi W]] | ||
Current revision
The E. coli class-II CAP-dependent transcription activation complex at the state 1 architecture
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