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1hk8

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<StructureSection load='1hk8' size='340' side='right'caption='[[1hk8]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
<StructureSection load='1hk8' size='340' side='right'caption='[[1hk8]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1hk8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1h77 1h77]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HK8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HK8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1hk8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1h77 1h77]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HK8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HK8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DGT:2-DEOXYGUANOSINE-5-TRIPHOSPHATE'>DGT</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1h78|1h78]], [[1h79|1h79]], [[1h7a|1h7a]], [[1h7b|1h7b]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DGT:2-DEOXYGUANOSINE-5-TRIPHOSPHATE'>DGT</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-triphosphate_reductase Ribonucleoside-triphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.2 1.17.4.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hk8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hk8 OCA], [https://pdbe.org/1hk8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hk8 RCSB], [https://www.ebi.ac.uk/pdbsum/1hk8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hk8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hk8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hk8 OCA], [http://pdbe.org/1hk8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hk8 RCSB], [http://www.ebi.ac.uk/pdbsum/1hk8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hk8 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NRDD_BPT4 NRDD_BPT4]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bpt4]]
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[[Category: Escherichia virus T4]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ribonucleoside-triphosphate reductase]]
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[[Category: Andersson J]]
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[[Category: Andersson, J]]
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[[Category: Larsson K-M]]
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[[Category: Larsson, K M]]
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[[Category: Logan DT]]
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[[Category: Logan, D T]]
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[[Category: Nordlund P]]
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[[Category: Nordlund, P]]
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[[Category: Sjoeberg B-M]]
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[[Category: Sjoeberg, B M]]
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[[Category: Allosteric regulation]]
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[[Category: Oxidoreductase]]
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[[Category: Reductase]]
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[[Category: Substrate specificity]]
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Current revision

STRUCTURAL BASIS FOR ALLOSTERIC SUBSTRATE SPECIFICITY REGULATION IN CLASS III RIBONUCLEOTIDE REDUCTASES: NRDD IN COMPLEX WITH DGTP

PDB ID 1hk8

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