1d76

<table><tr><td colspan='2'>[[1d76]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D76 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1D76 FirstGlance]. <br>

</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=1AP:2,6-DIAMINOPURINE+NUCLEOTIDE'>1AP</scene>, <scene name='pdbligand=DU:2-DEOXYURIDINE-5-MONOPHOSPHATE'>DU</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1d76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d76 OCA], [http://pdbe.org/1d76 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1d76 RCSB], [http://www.ebi.ac.uk/pdbsum/1d76 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1d76 ProSAT]</span></td></tr>

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== Publication Abstract from PubMed ==

The crystal and molecular structure of d(CGUA'CG)2 (where A' is 2-aminoadenine) has been determined and refined to an R factor of 13.8% for data 8.0-1.3 A. The structure is very similar to the original Z-DNA structures with the sequence d(CGCGCG)2 [Gessner, R. V., Frederick, C. A., Quigley, G. J., Rich, A., &amp; Wang, A. H.-J. (1989) J. Biol. Chem. 264, 7921] and shows that the substitution of 2-aminoadenine-uracil base pairs in the two central steps is consistent with Z-DNA formation. In addition, we show how waters mediating intermolecular interactions may help to explain the ZI-ZII conformational pattern found in many Z-DNA structures.

Crystal and molecular structure of a DNA fragment containing a 2-aminoadenine modification: the relationship between conformation, packing, and hydration in Z-DNA hexamers.,Schneider B, Ginell SL, Jones R, Gaffney B, Berman HM Biochemistry. 1992 Oct 13;31(40):9622-8. PMID:1390739<ref>PMID:1390739</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>

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<div class="pdbe-citations 1d76" style="background-color:#fffaf0;"></div>

== References ==

<references/>

[[Category: Berman, H M]]

[[Category: Gaffney, B]]

[[Category: Ginell, S L]]

[[Category: Jones, R]]

[[Category: Schneider, B]]

[[Category: Z-dna]]