1yis
From Proteopedia
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<StructureSection load='1yis' size='340' side='right'caption='[[1yis]], [[Resolution|resolution]] 2.40Å' scene=''> | <StructureSection load='1yis' size='340' side='right'caption='[[1yis]], [[Resolution|resolution]] 2.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[1yis]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1yis]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YIS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1YIS FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> |
- | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1yis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1yis OCA], [https://pdbe.org/1yis PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1yis RCSB], [https://www.ebi.ac.uk/pdbsum/1yis PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1yis ProSAT], [https://www.topsan.org/Proteins/SECSG/1yis TOPSAN]</span></td></tr> | |
- | + | ||
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
- | [ | + | [https://www.uniprot.org/uniprot/PUR8_CAEEL PUR8_CAEEL] Catalyzes two non-sequential steps in de novo AMP synthesis: converts (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate (SAICAR) to fumarate plus 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide, and thereby also contributes to de novo IMP synthesis, and converts succinyladenosine monophosphate (SAMP) to AMP and fumarate. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yi/1yis_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yi/1yis_consurf.spt"</scriptWhenChecked> | ||
- | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> |
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Caenorhabditis elegans]] |
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[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: An | + | [[Category: An J]] |
- | [[Category: Arabshahi | + | [[Category: Arabshahi A]] |
- | [[Category: Bray | + | [[Category: Bray T]] |
- | [[Category: Cao | + | [[Category: Cao Z]] |
- | [[Category: Chen | + | [[Category: Chen Y-J]] |
- | [[Category: Delucas | + | [[Category: Delucas L]] |
- | [[Category: Gray | + | [[Category: Gray R]] |
- | [[Category: Huang | + | [[Category: Huang W]] |
- | [[Category: Johnson | + | [[Category: Johnson D]] |
- | [[Category: Karpova | + | [[Category: Karpova E]] |
- | [[Category: Li | + | [[Category: Li S]] |
- | [[Category: Lu | + | [[Category: Lu S]] |
- | [[Category: Luan | + | [[Category: Luan C-H]] |
- | [[Category: Luo | + | [[Category: Luo D]] |
- | [[Category: Luo | + | [[Category: Luo M]] |
- | [[Category: McKinstry | + | [[Category: McKinstry A]] |
- | [[Category: Qiu | + | [[Category: Qiu S]] |
- | + | [[Category: Schormann N]] | |
- | [[Category: Schormann | + | [[Category: Shang Q]] |
- | [[Category: Shang | + | [[Category: Symersky J]] |
- | [[Category: Symersky | + | [[Category: Tsao J]] |
- | [[Category: Tsao | + | [[Category: Zhang Y]] |
- | [[Category: Zhang | + | [[Category: Zhou J]] |
- | [[Category: Zhou | + | |
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Current revision
Structural genomics of Caenorhabditis elegans: adenylosuccinate lyase
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Categories: Caenorhabditis elegans | Large Structures | An J | Arabshahi A | Bray T | Cao Z | Chen Y-J | Delucas L | Gray R | Huang W | Johnson D | Karpova E | Li S | Lu S | Luan C-H | Luo D | Luo M | McKinstry A | Qiu S | Schormann N | Shang Q | Symersky J | Tsao J | Zhang Y | Zhou J