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2l4e
From Proteopedia
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==NMR structure of the UBA domain of S. cerevisiae Dcn1== | ==NMR structure of the UBA domain of S. cerevisiae Dcn1== | ||
| - | <StructureSection load='2l4e' size='340' side='right'caption='[[2l4e | + | <StructureSection load='2l4e' size='340' side='right'caption='[[2l4e]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2l4e]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2l4e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L4E FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l4e OCA], [https://pdbe.org/2l4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l4e RCSB], [https://www.ebi.ac.uk/pdbsum/2l4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l4e ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/DCN1_YEAST DCN1_YEAST] Required for neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. Does not act by preventing deneddylation, but rather facilitates neddylation, possibly by acting with HRT1/RBX1 to recruit the Nedd8-charged E2 UBC12 to the cullin component of SCF-type complexes.<ref>PMID:15988528</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Atcc 18824]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Burschowsky | + | [[Category: Saccharomyces cerevisiae]] |
| - | [[Category: Mattle | + | [[Category: Burschowsky D]] |
| - | [[Category: Peter | + | [[Category: Mattle D]] |
| - | [[Category: Rudolf | + | [[Category: Peter M]] |
| - | [[Category: Wider | + | [[Category: Rudolf F]] |
| - | + | [[Category: Wider G]] | |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
NMR structure of the UBA domain of S. cerevisiae Dcn1
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