1z6o

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<StructureSection load='1z6o' size='340' side='right'caption='[[1z6o]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
<StructureSection load='1z6o' size='340' side='right'caption='[[1z6o]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1z6o]] is a 24 chain structure with sequence from [http://en.wikipedia.org/wiki/Trichoplusia_ni Trichoplusia ni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z6O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1Z6O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1z6o]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichoplusia_ni Trichoplusia ni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z6O FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.91&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1z6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z6o OCA], [http://pdbe.org/1z6o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1z6o RCSB], [http://www.ebi.ac.uk/pdbsum/1z6o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1z6o ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z6o OCA], [https://pdbe.org/1z6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z6o RCSB], [https://www.ebi.ac.uk/pdbsum/1z6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z6o ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q52SA8_TRINI Q52SA8_TRINI]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity).[RuleBase:RU361145] [[http://www.uniprot.org/uniprot/Q52SA9_TRINI Q52SA9_TRINI]] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity).[RuleBase:RU361145]
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[https://www.uniprot.org/uniprot/FRIL_TRINI FRIL_TRINI] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation (By similarity). Ferritin is composed of a heavy (H) chain which is responsible for the oxidation and uptake of ferrous iron, and a light (L) chain which facilitates the nucleation of the ferrihydrite iron core (Probable).[RuleBase:RU361145]<ref>PMID:15896348</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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<jmolCheckbox>
<jmolCheckbox>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z6/1z6o_consurf.spt"</scriptWhenChecked>
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z6/1z6o_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Trichoplusia ni]]
[[Category: Trichoplusia ni]]
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[[Category: Bjorkman, P J]]
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[[Category: Bjorkman PJ]]
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[[Category: Hamburger, A E]]
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[[Category: Hamburger AE]]
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[[Category: Hamburger, P]]
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[[Category: Hamburger P]]
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[[Category: Hamburger, Z A]]
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[[Category: Hamburger ZA]]
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[[Category: West, A P]]
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[[Category: West Jr AP]]
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[[Category: Iron storage]]
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[[Category: Metal binding protein]]
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Current revision

Crystal Structure of Trichoplusia ni secreted ferritin

PDB ID 1z6o

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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