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| | <StructureSection load='1zbb' size='340' side='right'caption='[[1zbb]], [[Resolution|resolution]] 9.00Å' scene=''> | | <StructureSection load='1zbb' size='340' side='right'caption='[[1zbb]], [[Resolution|resolution]] 9.00Å' scene=''> |
| | == Structural highlights == | | == Structural highlights == |
| - | <table><tr><td colspan='2'>[[1zbb]] is a 18 chain structure with sequence from [http://en.wikipedia.org/wiki/African_clawed_frog African clawed frog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZBB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ZBB FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[1zbb]] is a 18 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZBB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZBB FirstGlance]. <br> |
| - | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1kx5|1kx5]]</td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 9Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1zbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zbb OCA], [http://pdbe.org/1zbb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1zbb RCSB], [http://www.ebi.ac.uk/pdbsum/1zbb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1zbb ProSAT]</span></td></tr> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zbb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zbb OCA], [https://pdbe.org/1zbb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zbb RCSB], [https://www.ebi.ac.uk/pdbsum/1zbb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zbb ProSAT]</span></td></tr> |
| | </table> | | </table> |
| | == Function == | | == Function == |
| - | [[http://www.uniprot.org/uniprot/H2B11_XENLA H2B11_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H4_XENLA H4_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H32_XENLA H32_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [[http://www.uniprot.org/uniprot/H2A1_XENLA H2A1_XENLA]] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | + | [https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| | == Evolutionary Conservation == | | == Evolutionary Conservation == |
| | [[Image:Consurf_key_small.gif|200px|right]] | | [[Image:Consurf_key_small.gif|200px|right]] |
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| | __TOC__ | | __TOC__ |
| | </StructureSection> | | </StructureSection> |
| - | [[Category: African clawed frog]] | |
| | [[Category: Large Structures]] | | [[Category: Large Structures]] |
| - | [[Category: Duda, S]] | + | [[Category: Xenopus laevis]] |
| - | [[Category: Richmond, T J]] | + | [[Category: Duda S]] |
| - | [[Category: Sargent, D F]] | + | [[Category: Richmond TJ]] |
| - | [[Category: Schalch, T]] | + | [[Category: Sargent DF]] |
| - | [[Category: Chromatin]] | + | [[Category: Schalch T]] |
| - | [[Category: Chromatin fiber]]
| + | |
| - | [[Category: Histone]]
| + | |
| - | [[Category: Nucleoprotein]]
| + | |
| - | [[Category: Nucleosome]]
| + | |
| - | [[Category: Nucleosome core]]
| + | |
| - | [[Category: Protein-dna complex]]
| + | |
| - | [[Category: Protein-dna interaction]]
| + | |
| - | [[Category: Structural protein-dna complex]]
| + | |
| - | [[Category: Supercoiled dna]]
| + | |
| - | [[Category: Tetranucleosome]]
| + | |
