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Symporter 3D structures

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(New page: == 3D Structures of symporter == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *D-xylose/H+ symporter **4ja4...)
Current revision (10:18, 11 December 2023) (edit) (undo)
 
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== 3D Structures of symporter ==
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} - For a general description of the protein see [[Symporter]]
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+
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
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**[[4gby]] – EcSymp + xylose <BR />
**[[4gby]] – EcSymp + xylose <BR />
**[[4gbz]], [[4gc0]] – EcSymp + glucose derivative<BR />
**[[4gbz]], [[4gc0]] – EcSymp + glucose derivative<BR />
 +
 +
*Galactonate-proton symporter
 +
 +
**[[6e9o]] – EcSymp (mutant) + galactonate<BR />
 +
**[[6e9n]] – EcSymp + gluconate<BR />
*Di-or tripeptide/H+ symporter
*Di-or tripeptide/H+ symporter
-
**[[4ja4]], [[4xni]], [[4xnj]], [[4d2b]], [[4aps]], [[5d6k]], [[5mmt]], [[5d6k]], [[5oxo]], [[5oxp]], [[5oxq]], [[6eia]], [[6fmr]], [[6fmy]] – StSymp – ''Streptococcus thermophilus''<BR />
+
**[[4ja4]], [[4xni]], [[4xnj]], [[4d2b]], [[4aps]], [[5d6k]], [[5mmt]], [[5d6k]], [[5oxo]], [[5oxp]], [[5oxq]], [[6eia]], [[6fmr]], [[6fmy]], [[6yog]], [[6yof]], [[7ac6]] – StSymp – ''Streptococcus thermophilus''<BR />
**[[4d2d]], [[6ghj]] – StSymp + tripeptide<BR />
**[[4d2d]], [[6ghj]] – StSymp + tripeptide<BR />
**[[4d2c]], [[5d58]], [[5d59]], [[5oxk]], [[5oxl]], [[5oxm]], [[5oxn]] – StSymp + dipeptide<BR />
**[[4d2c]], [[5d58]], [[5d59]], [[5oxk]], [[5oxl]], [[5oxm]], [[5oxn]] – StSymp + dipeptide<BR />
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**[[4n7w]] – YfSymp – ''Yersinia frederiksenii''<BR />
**[[4n7w]] – YfSymp – ''Yersinia frederiksenii''<BR />
-
**[[4n7x]] – YfSymp (mutant) <BR />
+
**[[4n7x]], [[7cyg]], [[7cyk]] – YfSymp (mutant) <BR />
**[[3zuy]] – Symp - ''Neisseria meningitidis''<BR />
**[[3zuy]] – Symp - ''Neisseria meningitidis''<BR />
**[[3zux]] – Symp (mutant) <BR />
**[[3zux]] – Symp (mutant) <BR />
Line 46: Line 49:
*Glucose/Na+ symporter
*Glucose/Na+ symporter
 +
**[[7sl8]], [[7sla]] – hSymp 1 + nanobody – Cryo EM<BR />
 +
**[[7vsi]] – hSymp 2 + PDZK1-interacting protein + drug<BR />
**[[2xq2]] – VpSymp (mutant) – ''Vibrio parahaemolyticus''<BR />
**[[2xq2]] – VpSymp (mutant) – ''Vibrio parahaemolyticus''<BR />
**[[3dh4]] – VpSymp + galactose <BR />
**[[3dh4]] – VpSymp + galactose <BR />
Line 52: Line 57:
*Citrate/Na+ symporter
*Citrate/Na+ symporter
 +
**[[7jsj]] , [[7jsk]] – hSymp – Cryo EM<BR />
**[[5a1s]] – Symp + citrate + Na – ''Salmonella enterica''<BR />
**[[5a1s]] – Symp + citrate + Na – ''Salmonella enterica''<BR />
**[[5x9r]], [[5xas]], [[5xat]] – KpSymp + citrate + Na – ''Klebsiella pneumoniae''<BR />
**[[5x9r]], [[5xas]], [[5xat]] – KpSymp + citrate + Na – ''Klebsiella pneumoniae''<BR />
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*Sodium/alanine symporter
*Sodium/alanine symporter
-
**[[6csf]], [[6cse]] – Symp + antibody + alanine – ''Methanococcus maripaludis''<BR />
+
**[[6csf]], [[6cse]] – Symp + antibody + Ala – ''Methanococcus maripaludis''<BR />
-
*Sodium/aspartate symporter
+
*Sodium/aspartate symporter or Glt
-
**[[6bat]] – PhSymp + aspartate – ''Pyrococcus horikoshi''i<BR />
+
**[[6bat]] – PhSymp + Asp – ''Pyrococcus horikoshi''i<BR />
 +
**[[6wyk]], [[6wyl]] – PhSymp (mutant) + Asp – Cryo EM<BR />
 +
**[[7ahk]] – PhSymp + Na<BR />
 +
**[[6uwl]], [[6uwf]], [[7ugd]], [[7ugx]], [[7uh3]], [[7uh6]] – PhSymp + Asp + Na – Cryo EM<BR />
 +
**[[6ctf]], [[6x01]] – PhSymp (mutant) + Asp + Na <BR />
 +
**[[7rcp]], [[7ugv]] – PhSymp (mutant) + Asp + Na – Cryo EM<BR />
 +
**[[6wzb]] – PhSymp (mutant) + Asp + Na + Hg<BR />
 +
**[[7ug0]] [[7ugj]] – PhSymp (mutant) + Asp derivative + Na – Cryo EM<BR />
**[[6bav]], [[6bau]] – PhSymp (mutant) + cysteine derivative<BR />
**[[6bav]], [[6bau]] – PhSymp (mutant) + cysteine derivative<BR />
-
**[[6bmi]] – PhSymp (mutant) + serine<BR />
+
**[[6bmi]] – PhSymp (mutant) + Ser<BR />
*Sodium/glutamate symporter
*Sodium/glutamate symporter
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**[[4p6h]], [[4p3j]], [[4p1a]], [[3v8g]], [[3v8f]] – PhSymp <BR />
**[[4p6h]], [[4p3j]], [[4p1a]], [[3v8g]], [[3v8f]] – PhSymp <BR />
-
*Neurotransmitter/leucine symporter LeuT
+
*Neurotransmitter/leucine or Neurotransmitter/Na+ symporter LeuT
-
**[[5jaf]], [[5jae]] – AaSymp - ''Aquifex aeolicus''<BR />
+
**[[5jaf]], [[5jae]], [[6xwm]], [[7dii]], [[7dix]] – AaSymp - ''Aquifex aeolicus''<BR />
**[[5jag]] – AaSymp (mutant) <BR />
**[[5jag]] – AaSymp (mutant) <BR />
**[[3gjd]] – AaSymp + Na <BR />
**[[3gjd]] – AaSymp + Na <BR />
-
**[[3f48]] – AaSymp + alaine + Na<BR />
+
**[[3f48]], [[7lqj]] – AaSymp + Ala + Na<BR />
-
**[[3tu0]] – AaSymp (mutant) + alanine + Na <BR />
+
**[[3tu0]], [[7lqk]], [[7lql]] – AaSymp (mutant) + Ala + Na <BR />
**[[3f4j]] – AaSymp + glycine + Na<BR />
**[[3f4j]] – AaSymp + glycine + Na<BR />
-
**[[2a65]], [[3f3e]], [[3usg]], [[3usi]], [[3usj]], [[3usk]] – AaSymp + leucine + Na<BR />
+
**[[2a65]], [[3f3e]], [[3usg]], [[3usi]], [[3usj]], [[3usk]], [[6nle]], [[8ft4]], [[8ft5]] – AaSymp + Leu + Na<BR />
-
**[[3mpn]], [[3mpq]], [[3gjc]], [[4hmk]], [[4hod]], [[4fxz]] – AaSymp (mutant) + leucine + Na<BR />
+
**[[3mpn]], [[3mpq]], [[3gjc]], [[4hmk]], [[4hod]], [[4fxz]], [[7dj1]], [[7dj2]], [[7djc]],– AaSymp (mutant) + leucine + Na<BR />
-
**[[3f3a]] – AaSymp + tryptophan + Na <BR />
+
**[[3qs4]], [[3qs5]], [[3qs6]] – AaSymp (mutant) + Trp + Na <BR />
-
**[[3qs4]], [[3qs5]], [[3qs6]] – AaSymp (mutant) + tryptophan + Na <BR />
+
**[[3f3c]] – AaSymp + Phe + Na <BR />
-
**[[3f3c]] – AaSymp + phenylalanine + Na <BR />
+
**[[3f3d]], [[3f4i]], [[3usl]], [[3usm]], [[3uso]] – AaSymp + Met derivative + Na <BR />
-
**[[3f3d]], [[3f4i]], [[3usl]], [[3usm]], [[3uso]] – AaSymp + methionine derivative + Na <BR />
+
**[[4fy0]] – AaSymp (mutant) + Met + Na <BR />
-
**[[4fy0]] – AaSymp (mutant) + methionine + Na <BR />
+
**[[2qei]] – AaSymp + alaine + clomipramine + Na<BR />
**[[2qei]] – AaSymp + alaine + clomipramine + Na<BR />
**[[3gwu]] – AaSymp + sertraline + Na<BR />
**[[3gwu]] – AaSymp + sertraline + Na<BR />
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**[[5dwy]], [[4ky0]] – TkSymp – ''Thermococcus kodakarensis''<BR />
**[[5dwy]], [[4ky0]] – TkSymp – ''Thermococcus kodakarensis''<BR />
-
**[[5e9s]] – TkSymp + aspartate<BR />
+
**[[6xwr]] – TkSymp – Cryo EM<BR />
-
**[[4oyf]] – PhSymp - ''Pyrococcus horikishii'' <BR />
+
**[[5e9s]], [[6r7r]] – TkSymp + Asp<BR />
-
**[[2nwl]] – PhSymp (mutant) + aspartate<BR />
+
**[[8afa]] – TkSymp (mutant) + Asp – Cryo EMBR />
 +
**[[6zgb]], [[6zl4]], [[6zlh]] – TkSymp + photo switchable compound<BR />
 +
**[[6xwp]], [[6xwo]], [[6xwq]] – TkSymp + Asp – Cryo EM<BR />
 +
**[[7ngh]] – TkSymp + sybody + Asp – Cryo EM<BR />
 +
**[[6xwn]] – TkSymp + inhibitor – Cryo EM<BR />
 +
**[[4oyf]] – PhSymp<BR />
 +
**[[2nwl]] – PhSymp (mutant) + Asp<BR />
 +
 
 +
*Glycine/betaine symporter
 +
 
 +
**[[4llh]], [[3p03]], [[4c7r]], [[4doj]] – CgSymp (mutant) – ''Corynebacterium glutamicum''<BR />
 +
**[[4ain]] – CgSymp + trimethylglycine<BR />
 +
 
 +
*Sugar/H+ symporter
 +
 
 +
**[[8bb6]] – AtSymp 1 – ''Arabidopsis thaliana''<BR />
 +
**[[7aaq]], [[7aar]] – AtSymp 10 + antibody + alanine<BR />
 +
 
 +
*K+/H+ symporter
 +
 
 +
**[[8b70]] – BsSymp + K – ''Bacillus subtilis'' – Cryo EM<BR />
 +
**[[8b71]] – BsSymp + cAMP – Cryo EM<BR />
 +
 
 +
*K+/chloride symporter
 +
 
 +
**[[7d10]], [[7d8z]], [[7d90]], [[7ngb]] – hSymp – Cryo EM<BR />
 +
**[[6y5r]], [[6y5v]], [[7ain]], [[7aio]] – hSymp (mutant) – Cryo EM<BR />
 +
**[[6kkr]], [[6kku]] – hSymp + Cl – Cryo EM<BR />
 +
**[[6m1y]], [[6m22]], [[6m23]], [[6ukn]], [[7d99]] – hSymp + K + Cl – Cryo EM<BR />
 +
**[[7aip]], [[7aiq]], [[7air]] – hSymp + ATP – Cryo EM<BR />
 +
**[[7d14]] – mSymp – Cryo EM<BR />
 +
**[[6kkt]] – mSymp + K + Cl – Cryo EM<BR />
 +
**[[6vw9]], [[6vwa]] – Symp – ''Caenorhabditis elegans''<BR />
 +
 
 +
*Na+/K+/Cl symporter or NKCC1 or solute carrier family 12 member 2
 +
 
 +
**[[6pzt]], [[7s1z]] – hSymp (mutant) - Cryo EM<BR />
 +
**[[7mxo]] – hSymp + K + Cl - Cryo EM<BR />
 +
**[[7s1y]] – hSymp (mutant) + K + Cl - Cryo EM<BR />
 +
**[[7s1x]] – hSymp (mutant) + K + Cl + drug - Cryo EM<BR />
 +
**[[8fht]] – hSymp (mutant) + Na + Cl - Cryo EM<BR />
 +
**[[7n3n]], [[7sfl]] – hSymp + furosemide - Cryo EM<BR />
 +
**[[7smp]] – hSymp + K + inhibitor - Cryo EM<BR />
 +
**[[8fhq]] – hSymp (mutant) + Na + inhibitor - Cryo EM<BR />
 +
**[[8fhn]] – hSymp (mutant) + ATP + inhibitor - Cryo EM<BR />
 +
**[[8fho]] – hSymp (mutant) + Na + ATP + inhibitor - Cryo EM<BR />
 +
**[[7zgo]] – hSymp + Na + K + Cl + cholesterol derivative - Cryo EM<BR />
 +
**[[6npj]] – zfSymp – zebrafish - Cryo EM<BR />
 +
**[[6npk]] – zfSymp TM domain - Cryo EM<BR />
 +
**[[6nph]] – zfSymp TM domain + K + Cl - Cryo EM<BR />
 +
**[[6npl]] – zfSymp + K + Cl - Cryo EM<BR />
 +
**[[3g40]] – Symp – ''Methanosarcina acetivorans''<BR />
 +
 
 +
*Na+/iodide symporter
 +
 
 +
**[[7uuv]] – rSymp (mutant) – rat - Cryo EM<BR />
 +
**[[7uuz]] – rSymp (mutant) + Na + perrhenate - Cryo EM<BR />
 +
**[[7uv0]] – rSymp (mutant) + Na + I - Cryo EM<BR />
 +
 
 +
*Na+/bicarbonate symporter
 +
 
 +
**[[6caa]] – hSymp – Cryo EM<BR />
 +
 
 +
*Na+/monocarboxylate symporter
 +
 
 +
**[[7sl9]] – hSymp + nanobody – Cryo EM<BR />
 +
 
 +
*Na+/anion symporter
 +
 
 +
**[[6wtw]], [[6wu1]], [[6wu2]], [[6wu4]] – Symp – ''Lactobacillus acidophilus'' - Cryo EM<BR />
 +
**[[6wtx]] – VcSymp <BR />
 +
**[[6ww5]] – VcSymp + antibody – Cryo EM<BR />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Updated on 11-December-2023 - For a general description of the protein see Symporter

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Jaime Prilusky

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