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6jf5

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Current revision (10:07, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6jf5' size='340' side='right'caption='[[6jf5]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='6jf5' size='340' side='right'caption='[[6jf5]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6jf5]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JF5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JF5 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6jf5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JF5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JF5 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K2U:(3~{R},4~{R})-4-oxidanyl-3-(phenylmethyl)-4-(phenylmethylsulfanyl)butanoic+acid'>K2U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K2U:(3~{R},4~{R})-4-oxidanyl-3-(phenylmethyl)-4-(phenylmethylsulfanyl)butanoic+acid'>K2U</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jf5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jf5 OCA], [http://pdbe.org/6jf5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jf5 RCSB], [http://www.ebi.ac.uk/pdbsum/6jf5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jf5 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jf5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jf5 OCA], [https://pdbe.org/6jf5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jf5 RCSB], [https://www.ebi.ac.uk/pdbsum/6jf5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jf5 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/A0A098SKQ8_ACIBA A0A098SKQ8_ACIBA]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
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[https://www.uniprot.org/uniprot/A0A098SKQ8_ACIBA A0A098SKQ8_ACIBA] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.[HAMAP-Rule:MF_00163]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Acinetobacter baumannii]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Peptide deformylase]]
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[[Category: Ho TH]]
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[[Category: Ho, T H]]
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[[Category: Kang LW]]
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[[Category: Kang, L W]]
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[[Category: Lee IH]]
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[[Category: Lee, I H]]
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[[Category: Hydrolase]]
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Current revision

K2U bound crystal structure of class I type b peptide deformylase from Acinetobacter baumannii

PDB ID 6jf5

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