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6k9q

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==Structure of the native supercoiled hook as a universal joint==
==Structure of the native supercoiled hook as a universal joint==
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<StructureSection load='6k9q' size='340' side='right'caption='[[6k9q]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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<SX load='6k9q' size='340' side='right' viewer='molstar' caption='[[6k9q]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6k9q]] is a 26 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K9Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6K9Q FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6k9q]] is a 26 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6K9Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6K9Q FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6k9q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k9q OCA], [http://pdbe.org/6k9q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6k9q RCSB], [http://www.ebi.ac.uk/pdbsum/6k9q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6k9q ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6k9q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6k9q OCA], [https://pdbe.org/6k9q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6k9q RCSB], [https://www.ebi.ac.uk/pdbsum/6k9q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6k9q ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/FLGE_SALTY FLGE_SALTY]
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The Bacterial flagellar hook is a short supercoiled tubular structure made from a helical assembly of the hook protein FlgE. The hook acts as a universal joint that connects the flagellar basal body and filament, and smoothly transmits torque generated by the rotary motor to the helical filament propeller. In peritrichously flagellated bacteria, the hook allows the filaments to form a bundle behind the cell for swimming, and for the bundle to fall apart for tumbling. Here we report a native supercoiled hook structure at 3.6 A resolution by cryoEM single particle image analysis of the polyhook. The atomic model built into the three-dimensional (3D) density map reveals the changes in subunit conformation and intersubunit interactions that occur upon compression and extension of the 11 protofilaments during their smoke ring-like rotation. These observations reveal how the hook functions as a dynamic molecular universal joint with high bending flexibility and twisting rigidity.
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Structure of the native supercoiled flagellar hook as a universal joint.,Kato T, Makino F, Miyata T, Horvath P, Namba K Nat Commun. 2019 Nov 22;10(1):5295. doi: 10.1038/s41467-019-13252-9. PMID:31757961<ref>PMID:31757961</ref>
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==See Also==
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*[[Flagellar protein 3D structures|Flagellar protein 3D structures]]
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 6k9q" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
__TOC__
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</StructureSection>
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</SX>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Salmonella typhimurium]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Horvath, P]]
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[[Category: Horvath P]]
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[[Category: Kato, T]]
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[[Category: Kato T]]
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[[Category: Makino, F]]
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[[Category: Makino F]]
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[[Category: Miyata, T]]
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[[Category: Miyata T]]
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[[Category: Namba, K]]
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[[Category: Namba K]]
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[[Category: Flagella motor]]
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[[Category: Flge]]
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[[Category: Hook]]
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[[Category: Motor protein]]
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[[Category: Native structure]]
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[[Category: Supercoiled]]
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Current revision

Structure of the native supercoiled hook as a universal joint

6k9q, resolution 3.10Å

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