272d

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<StructureSection load='272d' size='340' side='right'caption='[[272d]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='272d' size='340' side='right'caption='[[272d]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[272d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=272D OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=272D FirstGlance]. <br>
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<table><tr><td colspan='2'>[[272d]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=272D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=272D FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=272d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=272d OCA], [http://pdbe.org/272d PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=272d RCSB], [http://www.ebi.ac.uk/pdbsum/272d PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=272d ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=272d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=272d OCA], [https://pdbe.org/272d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=272d RCSB], [https://www.ebi.ac.uk/pdbsum/272d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=272d ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
 
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== Publication Abstract from PubMed ==
 
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Nucleic acid triplexes are formed by sequence-specific interactions between single-stranded polynucleotides and the double helix. These triplexes are implicated in genetic recombination in vivo and have application to areas that include genome analysis and antigene therapy. Despite the importance of the triple helix, only limited high-resolution structural information is available. The x-ray crystal structure of the oligonucleotide d(GGCCAATTGG) is described; it was designed to contain the d(G middle dotGC)2 fragment and thus provide the basic repeat unit of a DNA triple helix. Parameters derived from this crystal structure have made it possible to construct models of both parallel and antiparallel triple helices.
 
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Parallel and antiparallel (G.GC)2 triple helix fragments in a crystal structure.,Vlieghe D, Van Meervelt L, Dautant A, Gallois B, Precigoux G, Kennard O Science. 1996 Sep 20;273(5282):1702-5. PMID:8781231<ref>PMID:8781231</ref>
 
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
 
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</div>
 
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<div class="pdbe-citations 272d" style="background-color:#fffaf0;"></div>
 
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== References ==
 
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<references/>
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Dautant, A]]
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[[Category: Dautant A]]
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[[Category: Gallois, B]]
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[[Category: Gallois B]]
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[[Category: Kennard, O]]
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[[Category: Kennard O]]
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[[Category: Meervelt, L Van]]
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[[Category: Precigoux G]]
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[[Category: Precigoux, G]]
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[[Category: Van Meervelt L]]
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[[Category: Vlieghe, D]]
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[[Category: Vlieghe D]]
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[[Category: B-dna]]
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[[Category: Dna]]
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[[Category: Double helix]]
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[[Category: Intermolecular base triplet]]
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[[Category: Overhanging base]]
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Current revision

PARALLEL AND ANTIPARALLEL (G.GC)2 TRIPLE HELIX FRAGMENTS IN A CRYSTAL STRUCTURE

PDB ID 272d

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