This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6y08
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Mouse thymidylate synthase cocrystallized with dUMP and soaked in sulfamethoxazole== | |
| + | <StructureSection load='6y08' size='340' side='right'caption='[[6y08]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6y08]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y08 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Y08 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.297Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=08D:SULFAMETHOXAZOLE'>08D</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6y08 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y08 OCA], [https://pdbe.org/6y08 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6y08 RCSB], [https://www.ebi.ac.uk/pdbsum/6y08 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6y08 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TYSY_MOUSE TYSY_MOUSE] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity). | ||
| - | + | ==See Also== | |
| - | + | *[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: | + | [[Category: Jarmula A]] |
| - | [[Category: | + | [[Category: Maj P]] |
| - | [[Category: Weiss | + | [[Category: Rode W]] |
| + | [[Category: Weiss MS]] | ||
| + | [[Category: Wilk P]] | ||
Current revision
Mouse thymidylate synthase cocrystallized with dUMP and soaked in sulfamethoxazole
| |||||||||||
Categories: Large Structures | Mus musculus | Jarmula A | Maj P | Rode W | Weiss MS | Wilk P
