6kmf
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==FimA type V pilus from P.gingivalis== | |
| + | <StructureSection load='6kmf' size='340' side='right'caption='[[6kmf]], [[Resolution|resolution]] 3.60Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6kmf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Porphyromonas_gingivalis_ATCC_33277 Porphyromonas gingivalis ATCC 33277]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KMF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KMF FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kmf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kmf OCA], [https://pdbe.org/6kmf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kmf RCSB], [https://www.ebi.ac.uk/pdbsum/6kmf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kmf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FIMA1_PORG3 FIMA1_PORG3] Structural subunit of the major fimbriae. These long, filamentous pili are attached to the cell surface; they mediate biofilm formation, adhesion onto host cells and onto other bacteria that are part of the oral microbiome (PubMed:9786913, PubMed:12593606, PubMed:15165251, PubMed:17675496, PubMed:17526848, PubMed:20530728, PubMed:27062925). They play an important role in the invasion of periodontal tissues (PubMed:12593606). Fimbriae and their constituents are major virulence factors. FimA proteins from different strains have highly divergent sequences, and this has been used for classification (PubMed:23809984). The sequence-based classification correlates with pathogenicity (PubMed:17675496).<ref>PMID:12593606</ref> <ref>PMID:15165251</ref> <ref>PMID:17526848</ref> <ref>PMID:17675496</ref> <ref>PMID:20530728</ref> <ref>PMID:23809984</ref> <ref>PMID:27062925</ref> <ref>PMID:9786913</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Pilin 3D structures|Pilin 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Porphyromonas gingivalis ATCC 33277]] | ||
| + | [[Category: Imada K]] | ||
| + | [[Category: Matsunami H]] | ||
| + | [[Category: Matthews M]] | ||
| + | [[Category: Nakayama K]] | ||
| + | [[Category: Shibata S]] | ||
| + | [[Category: Shoji M]] | ||
| + | [[Category: Wolf M]] | ||
Current revision
FimA type V pilus from P.gingivalis
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