6vw2
From Proteopedia
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(New page: '''Unreleased structure''' The entry 6vw2 is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils== | |
| - | + | <StructureSection load='6vw2' size='340' side='right'caption='[[6vw2]], [[Resolution|resolution]] 3.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6vw2]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VW2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VW2 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vw2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vw2 OCA], [https://pdbe.org/6vw2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vw2 RCSB], [https://www.ebi.ac.uk/pdbsum/6vw2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vw2 ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IAPP_HUMAN IAPP_HUMAN] Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.[https://www.uniprot.org/uniprot/SMT3_YEAST SMT3_YEAST] Not known; suppressor of MIF2 mutations. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Boyer DR]] | ||
| + | [[Category: Cao Q]] | ||
| + | [[Category: Eisenberg DS]] | ||
| + | [[Category: Sawaya MR]] | ||
Current revision
Cryo-EM structure of human islet amyloid polypeptide (hIAPP, or amylin) fibrils
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