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6vwb
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6vwb is ON HOLD Authors: Payliss, B., Houliston, S., Lemak, A., Arrowsmith, C.H., Wyatt, H.D.M. Description: Solution structure of the N-terminal h...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Solution structure of the N-terminal helix-hairpin-helix domain of human MUS81== | |
| + | <StructureSection load='6vwb' size='340' side='right'caption='[[6vwb]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6vwb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6VWB FirstGlance]. <br> | ||
| + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6vwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vwb OCA], [https://pdbe.org/6vwb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6vwb RCSB], [https://www.ebi.ac.uk/pdbsum/6vwb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6vwb ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MUS81_HUMAN MUS81_HUMAN] Interacts with EME1 and EME2 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.<ref>PMID:11741546</ref> <ref>PMID:12374758</ref> <ref>PMID:12686547</ref> <ref>PMID:12721304</ref> <ref>PMID:14617801</ref> <ref>PMID:15805243</ref> <ref>PMID:17289582</ref> <ref>PMID:19595721</ref> <ref>PMID:19596235</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Endonuclease 3D structures|Endonuclease 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Lemak | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| + | [[Category: Houliston S]] | ||
| + | [[Category: Lemak A]] | ||
| + | [[Category: Payliss B]] | ||
| + | [[Category: Wyatt HDM]] | ||
Current revision
Solution structure of the N-terminal helix-hairpin-helix domain of human MUS81
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