5wje

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==Crystal structure of Naa80 bound to a bisubstrate analogue==
==Crystal structure of Naa80 bound to a bisubstrate analogue==
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<StructureSection load='5wje' size='340' side='right'caption='[[5wje]], [[Resolution|resolution]] 1.77&Aring;' scene=''>
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<StructureSection load='5wje' size='340' side='right'caption='[[5wje]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5wje]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WJE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5WJE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5wje]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WJE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WJE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CMC:CARBOXYMETHYL+COENZYME+*A'>CMC</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.765&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMC:CARBOXYMETHYL+COENZYME+*A'>CMC</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Dmel\CG8481, CG8481-RB, CG8481, Dmel_CG8481 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wje OCA], [https://pdbe.org/5wje PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wje RCSB], [https://www.ebi.ac.uk/pdbsum/5wje PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wje ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5wje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wje OCA], [http://pdbe.org/5wje PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5wje RCSB], [http://www.ebi.ac.uk/pdbsum/5wje PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5wje ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NAA80_DROME NAA80_DROME] N-alpha-acetyltransferase that acetylates the amino terminal acidic residue of proteins devoid of initiator methionine (PubMed:29581307). Preferentially acts on proteins starting with Asp-Asp-Asp and Glu-Glu-Glu sequences (PubMed:29581307). In vitro, shows high activity towards N-terminal sequences starting with Met-Asp-Glu-Leu, Met-Glu-Glu-Glu and Met-Asp-Asp-Asp (PubMed:29581307).<ref>PMID:29581307</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Drome]]
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[[Category: Drosophila melanogaster]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arnesen, T]]
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[[Category: Arnesen T]]
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[[Category: Goris, M]]
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[[Category: Goris M]]
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[[Category: Magin, R S]]
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[[Category: Magin RS]]
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[[Category: Marmorstein, R]]
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[[Category: Marmorstein R]]
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[[Category: Acetyl-coa]]
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[[Category: Acetylation]]
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[[Category: Acetyltransferase]]
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[[Category: Gnat fold]]
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[[Category: Transferase]]
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Current revision

Crystal structure of Naa80 bound to a bisubstrate analogue

PDB ID 5wje

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