5wje
From Proteopedia
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==Crystal structure of Naa80 bound to a bisubstrate analogue== | ==Crystal structure of Naa80 bound to a bisubstrate analogue== | ||
- | <StructureSection load='5wje' size='340' side='right'caption='[[5wje]], [[Resolution|resolution]] 1. | + | <StructureSection load='5wje' size='340' side='right'caption='[[5wje]], [[Resolution|resolution]] 1.76Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[5wje]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5wje]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5WJE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5WJE FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.765Å</td></tr> |
- | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMC:CARBOXYMETHYL+COENZYME+*A'>CMC</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> |
- | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5wje FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5wje OCA], [https://pdbe.org/5wje PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5wje RCSB], [https://www.ebi.ac.uk/pdbsum/5wje PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5wje ProSAT]</span></td></tr> | |
- | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/NAA80_DROME NAA80_DROME] N-alpha-acetyltransferase that acetylates the amino terminal acidic residue of proteins devoid of initiator methionine (PubMed:29581307). Preferentially acts on proteins starting with Asp-Asp-Asp and Glu-Glu-Glu sequences (PubMed:29581307). In vitro, shows high activity towards N-terminal sequences starting with Met-Asp-Glu-Leu, Met-Glu-Glu-Glu and Met-Asp-Asp-Asp (PubMed:29581307).<ref>PMID:29581307</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Drosophila melanogaster]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: Arnesen | + | [[Category: Arnesen T]] |
- | [[Category: Goris | + | [[Category: Goris M]] |
- | [[Category: Magin | + | [[Category: Magin RS]] |
- | [[Category: Marmorstein | + | [[Category: Marmorstein R]] |
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Current revision
Crystal structure of Naa80 bound to a bisubstrate analogue
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