5r4h

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'''Unreleased structure'''
 
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The entry 5r4h is ON HOLD
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==PanDDA analysis group deposition -- CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF in complex with FMOPL000287a==
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<StructureSection load='5r4h' size='340' side='right'caption='[[5r4h]], [[Resolution|resolution]] 1.18&Aring;' scene=''>
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Authors: Talon, R., Krojer, T., Fairhead, M., Sethi, R., Bradley, A.R., Aimon, A., Collins, P., Brandao-Neto, J., Douangamath, A., Wright, N., MacLean, E., Renjie, Z., Dias, A., Brennan, P.E., Bountra, C., Arrowsmith, C.H., Edwards, A., von Delft, F.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5r4h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5R4H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5R4H FirstGlance]. <br>
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Description: PanDDA analysis group deposition --CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF in complex with FMOPL000287a
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.18&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=HWH:~{N}-[2-(5-fluoranyl-1~{H}-indol-3-yl)ethyl]ethanamide'>HWH</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr>
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[[Category: Aimon, A]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5r4h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5r4h OCA], [https://pdbe.org/5r4h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5r4h RCSB], [https://www.ebi.ac.uk/pdbsum/5r4h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5r4h ProSAT]</span></td></tr>
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[[Category: Collins, P]]
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</table>
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[[Category: Arrowsmith, C.H]]
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== Function ==
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[[Category: Brandao-Neto, J]]
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[https://www.uniprot.org/uniprot/BPTF_HUMAN BPTF_HUMAN] Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors.
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[[Category: Fairhead, M]]
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__TOC__
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[[Category: Von Delft, F]]
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</StructureSection>
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[[Category: Renjie, Z]]
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[[Category: Homo sapiens]]
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[[Category: Wright, N]]
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[[Category: Large Structures]]
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[[Category: Bradley, A.R]]
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[[Category: Aimon A]]
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[[Category: Talon, R]]
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[[Category: Arrowsmith CH]]
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[[Category: Brennan, P.E]]
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[[Category: Bountra C]]
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[[Category: Edwards, A]]
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[[Category: Bradley AR]]
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[[Category: Maclean, E]]
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[[Category: Brandao-Neto J]]
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[[Category: Douangamath, A]]
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[[Category: Brennan PE]]
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[[Category: Krojer, T]]
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[[Category: Collins P]]
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[[Category: Dias, A]]
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[[Category: Dias A]]
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[[Category: Sethi, R]]
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[[Category: Douangamath A]]
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[[Category: Bountra, C]]
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[[Category: Edwards A]]
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[[Category: Fairhead M]]
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[[Category: Krojer T]]
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[[Category: MacLean E]]
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[[Category: Renjie Z]]
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[[Category: Sethi R]]
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[[Category: Talon R]]
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[[Category: Wright N]]
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[[Category: Von Delft F]]

Current revision

PanDDA analysis group deposition -- CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF in complex with FMOPL000287a

PDB ID 5r4h

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