This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5r4i
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5r4i is ON HOLD Authors: Talon, R., Krojer, T., Fairhead, M., Sethi, R., Bradley, A.R., Aimon, A., Collins, P., Brandao-Neto, J., Douangamath, A., W...) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==PanDDA analysis group deposition -- CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF in complex with FMOPL000443a== | |
| - | + | <StructureSection load='5r4i' size='340' side='right'caption='[[5r4i]], [[Resolution|resolution]] 1.28Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5r4i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5R4I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5R4I FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.28Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=RUV:4-(acetylamino)-N-(4H-1,2,4-triazol-4-yl)benzamide'>RUV</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> |
| - | [[Category: Aimon | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5r4i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5r4i OCA], [https://pdbe.org/5r4i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5r4i RCSB], [https://www.ebi.ac.uk/pdbsum/5r4i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5r4i ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/BPTF_HUMAN BPTF_HUMAN] Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors. |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Aimon A]] |
| - | [[Category: | + | [[Category: Arrowsmith CH]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: | + | [[Category: Bradley AR]] |
| - | [[Category: | + | [[Category: Brandao-Neto J]] |
| - | [[Category: | + | [[Category: Brennan PE]] |
| - | [[Category: | + | [[Category: Collins P]] |
| - | [[Category: | + | [[Category: Dias A]] |
| - | [[Category: | + | [[Category: Douangamath A]] |
| - | [[Category: | + | [[Category: Edwards A]] |
| + | [[Category: Fairhead M]] | ||
| + | [[Category: Krojer T]] | ||
| + | [[Category: MacLean E]] | ||
| + | [[Category: Renjie Z]] | ||
| + | [[Category: Sethi R]] | ||
| + | [[Category: Talon R]] | ||
| + | [[Category: Wright N]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
PanDDA analysis group deposition -- CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF in complex with FMOPL000443a
| |||||||||||
Categories: Homo sapiens | Large Structures | Aimon A | Arrowsmith CH | Bountra C | Bradley AR | Brandao-Neto J | Brennan PE | Collins P | Dias A | Douangamath A | Edwards A | Fairhead M | Krojer T | MacLean E | Renjie Z | Sethi R | Talon R | Wright N | Von Delft F
