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6y43

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Current revision (13:19, 24 January 2024) (edit) (undo)
 
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<StructureSection load='6y43' size='340' side='right'caption='[[6y43]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
<StructureSection load='6y43' size='340' side='right'caption='[[6y43]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6y43]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y43 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Y43 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6y43]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6Y43 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6y43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y43 OCA], [http://pdbe.org/6y43 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6y43 RCSB], [http://www.ebi.ac.uk/pdbsum/6y43 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6y43 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6y43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y43 OCA], [https://pdbe.org/6y43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6y43 RCSB], [https://www.ebi.ac.uk/pdbsum/6y43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6y43 ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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[[http://www.uniprot.org/uniprot/ANGL6_HUMAN ANGL6_HUMAN]] Familial cerebral saccular aneurysm.
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[https://www.uniprot.org/uniprot/ANGL6_HUMAN ANGL6_HUMAN] Familial cerebral saccular aneurysm.
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ANGL6_HUMAN ANGL6_HUMAN]] May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure.
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[https://www.uniprot.org/uniprot/ANGL6_HUMAN ANGL6_HUMAN] May play a role in the wound healing process. May promote epidermal proliferation, remodeling and regeneration. May promote the chemotactic activity of endothelial cells and induce neovascularization. May counteract high-fat diet-induced obesity and related insulin resistance through increased energy expenditure.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Coker, J A]]
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[[Category: Coker JA]]
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[[Category: Krojer, T]]
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[[Category: Krojer T]]
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[[Category: Marsden, B D]]
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[[Category: Marsden BD]]
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[[Category: Midwood, K S]]
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[[Category: Midwood KS]]
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[[Category: Mutisya, J M]]
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[[Category: Mutisya JM]]
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[[Category: Structural genomic]]
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[[Category: Yue WW]]
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[[Category: Yue, W W]]
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[[Category: Damage-associated molecular pattern]]
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[[Category: Immune system]]
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[[Category: Sgc]]
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Current revision

Fibrinogen-like globe domain of human ANGPTL6

PDB ID 6y43

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