2dnv

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==Solution Structure of RSGI RUH-055, a Chromo Domain from Mus musculus cDNA==
==Solution Structure of RSGI RUH-055, a Chromo Domain from Mus musculus cDNA==
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<StructureSection load='2dnv' size='340' side='right'caption='[[2dnv]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2dnv' size='340' side='right'caption='[[2dnv]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2dnv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DNV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2DNV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2dnv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DNV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DNV FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dnv OCA], [http://pdbe.org/2dnv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2dnv RCSB], [http://www.ebi.ac.uk/pdbsum/2dnv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2dnv ProSAT], [http://www.topsan.org/Proteins/RSGI/2dnv TOPSAN]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2dnv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dnv OCA], [https://pdbe.org/2dnv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2dnv RCSB], [https://www.ebi.ac.uk/pdbsum/2dnv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2dnv ProSAT], [https://www.topsan.org/Proteins/RSGI/2dnv TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CBX8_MOUSE CBX8_MOUSE]] Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).
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[https://www.uniprot.org/uniprot/CBX8_MOUSE CBX8_MOUSE] Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Hirota, H]]
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[[Category: Hirota H]]
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[[Category: Kigawa, T]]
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[[Category: Kigawa T]]
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[[Category: Momen, A Z.M Ruhul]]
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[[Category: Ruhul Momen AZM]]
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[[Category: Structural genomic]]
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[[Category: Tomizawa T]]
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[[Category: Tomizawa, T]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Choromatin organization modifier]]
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[[Category: Chromo domain]]
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[[Category: Histone h3 tail]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Transcription]]
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Current revision

Solution Structure of RSGI RUH-055, a Chromo Domain from Mus musculus cDNA

PDB ID 2dnv

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