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4zfj

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Current revision (07:54, 10 May 2023) (edit) (undo)
 
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<StructureSection load='4zfj' size='340' side='right'caption='[[4zfj]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
<StructureSection load='4zfj' size='340' side='right'caption='[[4zfj]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4zfj]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZFJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ZFJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4zfj]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ZFJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ZFJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=XPE:3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL'>XPE</scene></td></tr>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=XPE:3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL'>XPE</scene></td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4zfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zfj OCA], [https://pdbe.org/4zfj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4zfj RCSB], [https://www.ebi.ac.uk/pdbsum/4zfj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4zfj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4zfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4zfj OCA], [http://pdbe.org/4zfj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4zfj RCSB], [http://www.ebi.ac.uk/pdbsum/4zfj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4zfj ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/EGTC_MYCS2 EGTC_MYCS2]] Catalyzes the hydrolysis of the gamma-glutamyl amide bond from N-(gamma-glutamyl)-[N(alpha),N(alpha),N(alpha)-trimethyl-L-histidinyl]-cysteine sulfoxide to produce hercynylcysteine sulfoxide.<ref>PMID:20420449</ref>
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[https://www.uniprot.org/uniprot/EGTC_MYCS2 EGTC_MYCS2] Catalyzes the hydrolysis of the gamma-glutamyl amide bond from N-(gamma-glutamyl)-[N(alpha),N(alpha),N(alpha)-trimethyl-L-histidinyl]-cysteine sulfoxide to produce hercynylcysteine sulfoxide.<ref>PMID:20420449</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Blankenfeldt, W]]
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[[Category: Mycolicibacterium smegmatis MC2 155]]
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[[Category: Seebeck, F P]]
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[[Category: Blankenfeldt W]]
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[[Category: Vit, A]]
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[[Category: Seebeck FP]]
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[[Category: Ergothioneine biosynthesis]]
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[[Category: Vit A]]
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[[Category: Hydrolase]]
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[[Category: Mycobacteria]]
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[[Category: Ntn hydrolase]]
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[[Category: Sulfur chemistry]]
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Current revision

Ergothioneine-biosynthetic Ntn hydrolase EgtC, apo form

PDB ID 4zfj

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