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4xoj

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<StructureSection load='4xoj' size='340' side='right'caption='[[4xoj]], [[Resolution|resolution]] 0.91&Aring;' scene=''>
<StructureSection load='4xoj' size='340' side='right'caption='[[4xoj]], [[Resolution|resolution]] 0.91&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4xoj]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XOJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XOJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4xoj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [https://en.wikipedia.org/wiki/Helianthus_annuus Helianthus annuus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XOJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XOJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.91&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xoj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xoj OCA], [http://pdbe.org/4xoj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xoj RCSB], [http://www.ebi.ac.uk/pdbsum/4xoj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xoj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xoj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xoj OCA], [https://pdbe.org/4xoj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xoj RCSB], [https://www.ebi.ac.uk/pdbsum/4xoj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xoj ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SFTI1_HELAN SFTI1_HELAN]] Inhibits trypsin, cathepsin G, elastase, chymotrypsin and thrombin. Does not inhibit factor Xa.<ref>PMID:10390350</ref>
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[https://www.uniprot.org/uniprot/TRY1_BOVIN TRY1_BOVIN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[Trypsin|Trypsin]]
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*[[Trypsin 3D structures|Trypsin 3D structures]]
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*[[Trypsin inhibitor|Trypsin inhibitor]]
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*[[Trypsin inhibitor 3D structures|Trypsin inhibitor 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: Helianthus annuus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Trypsin]]
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[[Category: Brzozowski K]]
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[[Category: Brzozowski, K]]
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[[Category: Debowski D]]
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[[Category: Debowski, D]]
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[[Category: Dubin G]]
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[[Category: Dubin, G]]
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[[Category: Gitlin A]]
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[[Category: Gitlin, A]]
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[[Category: Golik P]]
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[[Category: Golik, P]]
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[[Category: Grudnik P]]
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[[Category: Grudnik, P]]
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[[Category: Karna N]]
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[[Category: Karna, N]]
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[[Category: Legowska A]]
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[[Category: Legowska, A]]
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[[Category: Malicki S]]
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[[Category: Malicki, S]]
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[[Category: Rolka K]]
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[[Category: Rolka, K]]
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[[Category: Wladyka B]]
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[[Category: Wladyka, B]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor]]
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[[Category: Protease]]
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[[Category: Sfti]]
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[[Category: Splicing]]
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Current revision

Structure of bovine trypsin in complex with analogues of sunflower inhibitor 1 (SFTI-1)

PDB ID 4xoj

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