4cct

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<SX load='4cct' size='340' side='right' viewer='molstar' caption='[[4cct]], [[Resolution|resolution]] 4.50&Aring;' scene=''>
<SX load='4cct' size='340' side='right' viewer='molstar' caption='[[4cct]], [[Resolution|resolution]] 4.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4cct]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4azx 4azx]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CCT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CCT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4cct]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_1 Dengue virus 1]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4azx 4azx]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CCT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CCT FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4b03|4b03]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cct FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cct OCA], [http://pdbe.org/4cct PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4cct RCSB], [http://www.ebi.ac.uk/pdbsum/4cct PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4cct ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4cct FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cct OCA], [https://pdbe.org/4cct PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4cct RCSB], [https://www.ebi.ac.uk/pdbsum/4cct PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4cct ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/G3F5K5_9FLAV G3F5K5_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]
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[https://www.uniprot.org/uniprot/G3F5K5_9FLAV G3F5K5_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Dengue virus 1]]
[[Category: Dengue virus 1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Kostyuchenko, V A]]
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[[Category: Kostyuchenko VA]]
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[[Category: Lok, S M]]
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[[Category: Lok SM]]
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[[Category: Ng, T S]]
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[[Category: Ng TS]]
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[[Category: Tan, J L]]
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[[Category: Tan JL]]
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[[Category: Zhang, Q]]
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[[Category: Zhang Q]]
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[[Category: Flavivirus]]
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[[Category: Virus]]
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Current revision

Dengue 1 cryo-EM reconstruction

4cct, resolution 4.50Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

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