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4uif

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<SX load='4uif' size='340' side='right' viewer='molstar' caption='[[4uif]], [[Resolution|resolution]] 6.50&Aring;' scene=''>
<SX load='4uif' size='340' side='right' viewer='molstar' caption='[[4uif]], [[Resolution|resolution]] 6.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4uif]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Dengue_virus_2 Dengue virus 2] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UIF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UIF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4uif]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_2 Dengue virus 2] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UIF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UIF FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4uih|4uih]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uif OCA], [http://pdbe.org/4uif PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uif RCSB], [http://www.ebi.ac.uk/pdbsum/4uif PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uif ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uif FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uif OCA], [https://pdbe.org/4uif PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uif RCSB], [https://www.ebi.ac.uk/pdbsum/4uif PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uif ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/E0WXJ2_9FLAV E0WXJ2_9FLAV] Component of the viral RNA replication complex that functions in virion assembly and antagonizes the host immune response.[ARBA:ARBA00024317] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Fibriansah, G]]
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[[Category: Crowe Junior JE]]
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[[Category: Harris, E]]
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[[Category: Fibriansah G]]
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[[Category: Ibarra, K D]]
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[[Category: Harris E]]
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[[Category: Junior, J E.Crowe]]
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[[Category: Ibarra KD]]
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[[Category: Kostyuchenko, V A]]
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[[Category: Kostyuchenko VA]]
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[[Category: Lim, X N]]
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[[Category: Lim X-N]]
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[[Category: Lok, S M]]
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[[Category: Lok S-M]]
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[[Category: Ng, T S]]
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[[Category: Ng T-S]]
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[[Category: Ooi, J S.G]]
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[[Category: Ooi JSG]]
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[[Category: Silva, A M.de]]
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[[Category: Smith SA]]
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[[Category: Smith, S A]]
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[[Category: Tan JL]]
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[[Category: Tan, J L]]
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[[Category: Wang J]]
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[[Category: Wang, J]]
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[[Category: De Silva AM]]
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[[Category: Cryo-em]]
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[[Category: Dengue virus]]
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[[Category: Human antibody]]
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[[Category: Neutralization]]
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[[Category: Viral protein]]
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Current revision

Cryo-EM structure of Dengue virus serotype 2 in complex with antigen-binding fragments of human antibody 2D22

4uif, resolution 6.50Å

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