3a5x
From Proteopedia
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<SX load='3a5x' size='340' side='right' viewer='molstar' caption='[[3a5x]], [[Resolution|resolution]] 4.00Å' scene=''> | <SX load='3a5x' size='340' side='right' viewer='molstar' caption='[[3a5x]], [[Resolution|resolution]] 4.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3a5x]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3a5x]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A5X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A5X FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a5x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a5x OCA], [https://pdbe.org/3a5x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a5x RCSB], [https://www.ebi.ac.uk/pdbsum/3a5x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a5x ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/FLIC_SALTY FLIC_SALTY] Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3a5x ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3a5x ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | The bacterial flagellar filament is a helical propeller rotated by the flagellar motor for bacterial locomotion. The filament is a supercoiled assembly of a single protein, flagellin, and is formed by 11 protofilaments. For bacterial taxis, the reversal of motor rotation switches the supercoil between left- and right-handed, both of which arise from combinations of two distinct conformations and packing interactions of the L-type and R-type protofilaments. Here we report an atomic model of the L-type straight filament by electron cryomicroscopy and helical image analysis. Comparison with the R-type structure shows interesting features: an orientation change of the outer core domains (D1) against the inner core domains (D0) showing almost invariant orientation and packing, a conformational switching within domain D1, and the conformational flexibility of domains D0 and D1 with their spoke-like connection for tight molecular packing. | ||
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| - | Conformational change of flagellin for polymorphic supercoiling of the flagellar filament.,Maki-Yonekura S, Yonekura K, Namba K Nat Struct Mol Biol. 2010 Apr;17(4):417-22. Epub 2010 Mar 14. PMID:20228803<ref>PMID:20228803</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 3a5x" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Flagellar filament of bacteria|Flagellar filament of bacteria]] | ||
*[[Flagellin 3D structures|Flagellin 3D structures]] | *[[Flagellin 3D structures|Flagellin 3D structures]] | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</SX> | </SX> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Salmonella | + | [[Category: Salmonella enterica subsp. enterica serovar Typhimurium]] |
| - | [[Category: Maki-Yonekura | + | [[Category: Maki-Yonekura S]] |
| - | [[Category: Namba | + | [[Category: Namba K]] |
| - | [[Category: Yonekura | + | [[Category: Yonekura K]] |
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Current revision
L-type straight flagellar filament made of full-length flagellin
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