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5ooc

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<SX load='5ooc' size='340' side='right' viewer='molstar' caption='[[5ooc]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
<SX load='5ooc' size='340' side='right' viewer='molstar' caption='[[5ooc]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ooc]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OOC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OOC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ooc]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OOC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OOC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=9ZK:(4~{R},7~{R},10~{S},13~{S},15~{E},19~{S})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{H}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone'>9ZK</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=9ZK:(4~{R},7~{R},10~{S},13~{S},15~{E},19~{S})-10-(4-azanylbutyl)-4-(4-hydroxyphenyl)-7-(1~{H}-indol-3-ylmethyl)-8,13,15,19-tetramethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone'>9ZK</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5onv|5onv]], [[5ood|5ood]], [[5oof|5oof]], [[5ooe|5ooe]], [[6t1y|6t1y]], [[6t20|6t20]], [[6t23|6t23]], [[6t24|6t24]], [[6t25|6t25]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ooc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ooc OCA], [https://pdbe.org/5ooc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ooc RCSB], [https://www.ebi.ac.uk/pdbsum/5ooc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ooc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ooc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ooc OCA], [http://pdbe.org/5ooc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ooc RCSB], [http://www.ebi.ac.uk/pdbsum/5ooc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ooc ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT]] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
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[https://www.uniprot.org/uniprot/ACTS_RABIT ACTS_RABIT] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
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[[Category: Arndt, H D]]
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[[Category: Arndt H-D]]
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[[Category: Bieling, P]]
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[[Category: Bieling P]]
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[[Category: Funk, J]]
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[[Category: Funk J]]
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[[Category: Kuellmer, F]]
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[[Category: Kuellmer F]]
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[[Category: Merino, F]]
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[[Category: Merino F]]
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[[Category: Pospich, S]]
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[[Category: Pospich S]]
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[[Category: Raunser, S]]
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[[Category: Raunser S]]
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[[Category: Cell migration]]
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[[Category: Cytoskeleton]]
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[[Category: Filament stability]]
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[[Category: Nucleotide state]]
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[[Category: Structural protein]]
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Current revision

Cryo-EM structure of jasplakinolide-stabilized F-actin in complex with ADP

5ooc, resolution 3.60Å

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