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5r67
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==PanDDA analysis group deposition -- Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with FMOPL000589a== | |
| - | + | <StructureSection load='5r67' size='340' side='right'caption='[[5r67]], [[Resolution|resolution]] 1.52Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[5r67]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5R67 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5R67 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.52Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=S6V:1-[2-(2-oxidanylidenepyrrolidin-1-yl)ethyl]-3-phenyl-urea'>S6V</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | [[Category: Aimon | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5r67 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5r67 OCA], [https://pdbe.org/5r67 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5r67 RCSB], [https://www.ebi.ac.uk/pdbsum/5r67 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5r67 ProSAT]</span></td></tr> |
| - | [[Category: Arrowsmith | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/CPSF5_HUMAN CPSF5_HUMAN] Component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3'-processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5'-UGUA-3' elements within the pre-mRNA. Binds to, but does not hydrolyze mono- and di-adenosine nucleotides. May have a role in mRNA export.<ref>PMID:9659921</ref> <ref>PMID:8626397</ref> <ref>PMID:14690600</ref> <ref>PMID:20695905</ref> <ref>PMID:20479262</ref> <ref>PMID:21295486</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Huber | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Aimon A]] |
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Bradley AR]] | ||
| + | [[Category: Diaz-Saez L]] | ||
| + | [[Category: Edwards AM]] | ||
| + | [[Category: Fairhead M]] | ||
| + | [[Category: Huber KVM]] | ||
| + | [[Category: Krojer T]] | ||
| + | [[Category: Talon R]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
PanDDA analysis group deposition -- Crystal Structure of HUMAN CLEAVAGE FACTOR IM in complex with FMOPL000589a
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Categories: Homo sapiens | Large Structures | Aimon A | Arrowsmith CH | Bountra C | Bradley AR | Diaz-Saez L | Edwards AM | Fairhead M | Huber KVM | Krojer T | Talon R | Von Delft F
