Tryptophan synthase 3D structures
From Proteopedia
(Difference between revisions)
(New page: ==3D structures of tryptophan synthase== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *'''Tryptophan synthase α...) |
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==3D structures of tryptophan synthase== | ==3D structures of tryptophan synthase== | ||
- | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | + | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} - For a general description of the protein see [[Tryptophan synthase]] |
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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**[[5kmy]], [[5k9x]], [[6oky]] - TrpS α subunit – ''Legionella pneumophila''<br /> | **[[5kmy]], [[5k9x]], [[6oky]] - TrpS α subunit – ''Legionella pneumophila''<br /> | ||
**[[5n2p]] - SsTrpS α subunit – ''Sulfolobus solfataricus''<br /> | **[[5n2p]] - SsTrpS α subunit – ''Sulfolobus solfataricus''<br /> | ||
+ | **[[6oso]], [[6ouy]] - StTrpS α subunit – ''Salmonella typhimurium''<br /> | ||
+ | **[[6qky]] - SpTrpS α subunit – ''Streptococcus pneumoniae''<br /> | ||
*Tryptophan synthase α binary complex | *Tryptophan synthase α binary complex | ||
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**[[2dh6]] - EcTrpS β subunit - ''Escherichia coli''<br /> | **[[2dh6]] - EcTrpS β subunit - ''Escherichia coli''<br /> | ||
**[[2o2e]], [[2o2j]] - MtTrpS β subunit – ''Mycobacterium tuberculosis''<br /> | **[[2o2e]], [[2o2j]] - MtTrpS β subunit – ''Mycobacterium tuberculosis''<br /> | ||
- | **[[1v8z]] - PfTrpS β1 subunit <br /> | + | **[[1v8z]], [[5vm5]], [[6am7]], [[6am9]], [[6amc]], [[6amh]], [[6cuv]] - PfTrpS β1 subunit <br /> |
**[[4neg]] - TrpS β subunit – ''Bacillus anthracis''<br /> | **[[4neg]] - TrpS β subunit – ''Bacillus anthracis''<br /> | ||
- | **[[4qys]], [[6hte]] - SsTrpS β2 subunit<br /> | ||
*Tryptophan synthase β complex | *Tryptophan synthase β complex | ||
**[[2dh5]] - EcTrpS β subunit + PLP<br /> | **[[2dh5]] - EcTrpS β subunit + PLP<br /> | ||
- | **[[ | + | **[[4qys]], [[6hte]] - SsTrpS β2 subunit + PLP<br /> |
**[[5dvz]] - PfTrpS β1 subunit + PLP derivative <br /> | **[[5dvz]] - PfTrpS β1 subunit + PLP derivative <br /> | ||
- | **[[6am7]], [[6amc]], [[6cuv]] - PfTrpS β1 subunit (mutant) + PLP derivative <br /> | + | **[[6am7]], [[6amc]], [[6cuv]], [[7rnq]] - PfTrpS β1 subunit (mutant) + PLP derivative <br /> |
**[[5dw0]] - PfTrpS β1 subunit + Ser derivative <br /> | **[[5dw0]] - PfTrpS β1 subunit + Ser derivative <br /> | ||
**[[5dw3]] - PfTrpS β1 subunit + PLP derivative + Trp<br /> | **[[5dw3]] - PfTrpS β1 subunit + PLP derivative + Trp<br /> | ||
**[[6am8]], [[6ami]] - PfTrpS β1 subunit (mutant) + PLP derivative + Trp<br /> | **[[6am8]], [[6ami]] - PfTrpS β1 subunit (mutant) + PLP derivative + Trp<br /> | ||
**[[5t6m]] - PfTrpS β1 subunit + PLP derivative + Trp derivative<br /> | **[[5t6m]] - PfTrpS β1 subunit + PLP derivative + Trp derivative<br /> | ||
+ | **[[7rnp]], [[7rof]] - PfTrpS β1 subunit (mutant) + PLP derivative + Trp derivative<br /> | ||
+ | **[[6xsy]] - PfTrpS β1 subunit (mutant) + PLP derivative + inhibitor<br /> | ||
**[[5vm5]] - PfTrpS β1 subunit + PLP derivative + Ser derivative<br /> | **[[5vm5]] - PfTrpS β1 subunit + PLP derivative + Ser derivative<br /> | ||
**[[5ixj]] - PfTrpS β1 subunit + PLP derivative + Thr<br /> | **[[5ixj]] - PfTrpS β1 subunit + PLP derivative + Thr<br /> | ||
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**[[6cut]] - PfTrpS β1 subunit (mutant) + Trp analog <br /> | **[[6cut]] - PfTrpS β1 subunit (mutant) + Trp analog <br /> | ||
**[[6cuz]] - PfTrpS β1 subunit (mutant) + PLP derivative + ethylserine<br /> | **[[6cuz]] - PfTrpS β1 subunit (mutant) + PLP derivative + ethylserine<br /> | ||
+ | **[[8egy]], [[8egz]] - TmTrpS β1 subunit + PLP derivative – ''Thermotoga maritima''<br /> | ||
+ | **[[8eh0]] - TmTrpS β1 subunit + PLP derivative + quinoline derivative<br /> | ||
*'''Tryptophan synthase α+β subunits''' | *'''Tryptophan synthase α+β subunits''' | ||
**[[1wdw]] - PfTrpS α + β subunits <br /> | **[[1wdw]] - PfTrpS α + β subunits <br /> | ||
- | **[[ | + | **[[5tcf]] - MtTrpS α + β <br /> |
+ | **[[6wdu]], [[7a20]], [[7l5h]], [[7lev]] - StTrpS α + β <br /> | ||
+ | **[[7kq9]] - StTrpS α + β (mutant)<br /> | ||
+ | **[[6v82]] - TrpS α + β – ''Chlamydia trachomatis''<br /> | ||
*Tryptophan synthase α+β binary complex | *Tryptophan synthase α+β binary complex | ||
- | **[[1ttp]], [[1ttq]], [[1bks]], [[2wsy]], [[1kfk]] - StTrpS α + β + PLP | + | **[[1ttp]], [[1ttq]], [[1bks]], [[2wsy]], [[1kfk]], [[7l4d]], [[7lx1]], [[8b03]] - StTrpS α + β + PLP <br /> |
- | **[[1k7x]], [[2j9z]] - StTrpS α + β (mutant) + PLP<br /> | + | **[[6dz4]], [[8b05]], [[8b08]] - StTrpS α + β + PLP derivative<br /> |
- | **[[3pr2]], [[4hn4]], [[4hpj]], [[4hpx]], [[4ht3]], [[4kkx]] - StTrpS α + β + inhibitor<br /> | + | **[[1k7x]], [[2j9z]], [[7kmc]], [[7l47]] - StTrpS α + β (mutant) + PLP<br /> |
+ | **[[3pr2]], [[4hn4]], [[4hpj]], [[4hpx]], [[4ht3]], [[4kkx]], [[7kwv]], [[7kxc]], [[7kyt]], [[7l03]] - StTrpS α + β + inhibitor<br /> | ||
**[[1kfj]] - StTrpS α + β + pyridoxal-serine-monophsphate<br /> | **[[1kfj]] - StTrpS α + β + pyridoxal-serine-monophsphate<br /> | ||
**[[1a5a]], [[1k8x]] - StTrpS α (mutant) + β + PLP<br /> | **[[1a5a]], [[1k8x]] - StTrpS α (mutant) + β + PLP<br /> | ||
**[[1kfe]] - StTrpS α (mutant) + β + pyridoxal-serine-monophsphate<br /> | **[[1kfe]] - StTrpS α (mutant) + β + pyridoxal-serine-monophsphate<br /> | ||
- | **[[6o1h]], [[6dzo]], [[6duc]], [[6d0v]], [[6c73]] - StTrpS α + β (mutant) + inhibitor<br /> | + | **[[7ku9]], [[7l1h]], [[7lgx]], [[7mt4]], [[7mt5]], [[7mt6]] - StTrpS α + β + inhibitor<br /> |
- | **[[2j9y]] - StTrpS α + β (mutant) + enoic acid derivative<br /> | + | **[[6o1h]], [[6dzo]], [[6duc]], [[6d0v]], [[6c73]], [[6x0c]], [[7jmq]], [[7kbn]], [[7ki7]] - StTrpS α + β (mutant) + inhibitor<br /> |
+ | **[[2j9y]], [[7lt4]] - StTrpS α + β (mutant) + enoic acid derivative<br /> | ||
+ | **[[6xrh]], [[6xt0]] - StTrpS α + β (mutant) + IGP + Ala derivative<br /> | ||
+ | **[[7jqw]], [[7k5a]] - StTrpS α + β (mutant) + Ser <br /> | ||
**[[2tys]] - StTrpS α (mutant) + β (mutant) + Trp derivative<br /> | **[[2tys]] - StTrpS α (mutant) + β (mutant) + Trp derivative<br /> | ||
**[[5kzm]] - TrpS α + β + PLP derivative – ''Francisella tularensis''<br /> | **[[5kzm]] - TrpS α + β + PLP derivative – ''Francisella tularensis''<br /> | ||
- | **[[5kin]] - | + | **[[5kin]] - SpTrpS α + β + PLP derivative – ''Streptococcus pneumoniae''<br /> |
**[[5e0k]] - PfTrpS α + β + PLP derivative <br /> | **[[5e0k]] - PfTrpS α + β + PLP derivative <br /> | ||
**[[5ocw]], [[5tcg]], [[5tci]], [[5tcj]] - MtTrpS α + β + inhibitor<br /> | **[[5ocw]], [[5tcg]], [[5tci]], [[5tcj]] - MtTrpS α + β + inhibitor<br /> | ||
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**[[5tch]] - MtTrpS α + β (mutant) + PLP derivative <br /> | **[[5tch]] - MtTrpS α + β (mutant) + PLP derivative <br /> | ||
**[[5e0k]] - PfTrpS α + β + PLP derivative <br /> | **[[5e0k]] - PfTrpS α + β + PLP derivative <br /> | ||
+ | **[[5ey5]] - TrpS α + β + PLP - synthetic <br /> | ||
*Tryptophan synthase α+β ternary complex with PLP and inhibitor | *Tryptophan synthase α+β ternary complex with PLP and inhibitor | ||
- | **[[1a50]], [[1cw2]], [[1c9d]], [[1cx9]], [[1c8v]], [[1c29]], [[2cle]], [[2clh]], [[2cli]], [[2clk]], [[2cll]], [[2clm]], [[2clo]], [[2clf]], [[5bw6]], [[4zqc]], [[4y6g]], [[4xug]], [[4wx2]], [[5bw6]] - StTrpS α + β + inhibitor + PLP<br /> | + | **[[1a50]], [[1cw2]], [[1c9d]], [[1cx9]], [[1c8v]], [[1c29]], [[2cle]], [[2clh]], [[2cli]], [[2clk]], [[2cll]], [[2clm]], [[2clo]], [[2clf]], [[5bw6]], [[4zqc]], [[4y6g]], [[4xug]], [[4wx2]], [[5bw6]], [[6vnt]], [[6wx3]], [[6xin]], [[7kqf]], [[7lpf]], [[7lvx]], [[7ly8]], [[7m2l]], [[7m3s]], [[7me8]] - StTrpS α + β + inhibitor + PLP<br /> |
- | **[[ | + | **[[1fuy]], [[7jhw]], [[7kh6]] - StTrpS α + β (mutant) + inhibitor + PLP<br /> |
- | **[[ | + | **[[6xe3]] - StTrpS α + β (mutant) + inhibitor + PLP derivative<br /> |
*Tryptophan synthase α+β ternary complex with PLP and IGP derivatives | *Tryptophan synthase α+β ternary complex with PLP and IGP derivatives | ||
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**[[2tsy]] - StTrpS α (mutant) + β (mutant) + pyridoxal-serine-monophsphate + G3P | **[[2tsy]] - StTrpS α (mutant) + β (mutant) + pyridoxal-serine-monophsphate + G3P | ||
- | **[[1ubs]] - StTrpS α (mutant) + β (mutant) + | + | *Other TrpS α+β ternary complex |
+ | |||
+ | **[[6hul]] - SsTrpS α + β subunits + PLP + Ser<br /> | ||
+ | **[[8b06]] - StTrpS α + β + Ser + PLP<br /> | ||
+ | **[[7k0b]] - StTrpS α + β (mutant) + Ser + PLP<br /> | ||
+ | **[[1ubs]] - StTrpS α (mutant) + β (mutant) + Ser + PLP<br /> | ||
+ | **[[7jtt]], [[7ka1]] - StTrpS α + β (mutant) + Ser + inhibitor<br /> | ||
+ | **[[6vfd]] - StTrpS α + β + quinoid derivative + Ser<br /> | ||
+ | **[[6xnc]], [[6xoy]] - StTrpS α + β + IGP + Trp derivative<br /> | ||
+ | **[[7lut]] - StTrpS α + β + PLP + Trp <br /> | ||
+ | **[[6usa]] - MtTrpS α + β + PLP derivative + piperazine derivative<br /> | ||
*Tryptophan synthase α+β quaternary complex | *Tryptophan synthase α+β quaternary complex | ||
- | **[[1a5s]] - StTrpS α + β + | + | **[[1a5s]] - StTrpS α + β + Ser + inhibitor + PLP<br /> |
- | **[[5cgq]] - StTrpS α + β + Trp + inhibitor + PLP<br /> | + | **[[5cgq]], [[7lkl]], [[7ltp]] - StTrpS α + β + Trp + inhibitor + PLP<br /> |
+ | **[[7lv5]] - StTrpS α + β + His + inhibitor + PLP<br /> | ||
+ | |||
+ | **[[7jll]] - StTrpS α + β (mutant) + Trp + inhibitor + PLP<br /> | ||
**[[3cep]] - StTrpS α + β + G3P + indoline + PLP<br /> | **[[3cep]] - StTrpS α + β + G3P + indoline + PLP<br /> | ||
**[[6uap]], [[6ub9]], [[6dwe]], [[6e9p]] - MtTrpS α + β + malonate + inhibitor + PLP derivative<br /> | **[[6uap]], [[6ub9]], [[6dwe]], [[6e9p]] - MtTrpS α + β + malonate + inhibitor + PLP derivative<br /> | ||
+ | **[[6u6c]] - MtTrpS α + β + PLP derivative + sulfonamide derivative + Ala<br /> | ||
+ | |||
+ | *Dimethylallyl tryptophan synthase or tryptophan 6-prenyltransferase | ||
+ | |||
+ | **[[3i4z]] - AfDATrpS – ''Aspergillus fumigatus''<br /> | ||
+ | **[[3i4x]] - AfDATrpS + DMAPP + Trp<br /> | ||
+ | **[[4ld7]] - DATrpS + thiopyrophosphate – ''Neosartoria fischeri<''br /> | ||
+ | **[[6zs0]] - ScDATrpS – Stretptomyces coelicolor<br /> | ||
+ | **[[5inj]], [[6zrz]], [[7w8v]], [[7w8w]], [[7w8x]] - ScDATrpS + DMASPP + Trp<br /> | ||
+ | **[[7y8y]] - ScDATrpS + thiopyrophosphate + DMASPP + Trp<br /> | ||
+ | **[[6zry]] - MoDATrpS + Trp – ''Micromonospora olivasterospora''<br /> | ||
+ | **[[6zrx]] - MoDATrpS + DMAPP + Trp<br /> | ||
+ | |||
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] |
Current revision
3D structures of tryptophan synthase
Updated on 29-January-2024 - For a general description of the protein see Tryptophan synthase