This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


6jkg

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:13, 22 November 2023) (edit) (undo)
 
Line 1: Line 1:
-
==cholesterol-decarboxylating enzyme 1==
+
==The NAD+-free form of human NSDHL==
<StructureSection load='6jkg' size='340' side='right'caption='[[6jkg]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='6jkg' size='340' side='right'caption='[[6jkg]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[6jkg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JKG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JKG FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[6jkg]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JKG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JKG FirstGlance]. <br>
-
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NSDHL, H105E3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-beta-hydroxysteroid-4-alpha-carboxylate_3-dehydrogenase_(decarboxylating) 3-beta-hydroxysteroid-4-alpha-carboxylate 3-dehydrogenase (decarboxylating)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.170 1.1.1.170] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jkg OCA], [https://pdbe.org/6jkg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jkg RCSB], [https://www.ebi.ac.uk/pdbsum/6jkg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jkg ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jkg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jkg OCA], [http://pdbe.org/6jkg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jkg RCSB], [http://www.ebi.ac.uk/pdbsum/6jkg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jkg ProSAT]</span></td></tr>
+
</table>
</table>
== Disease ==
== Disease ==
-
[[http://www.uniprot.org/uniprot/NSDHL_HUMAN NSDHL_HUMAN]] CHILD syndrome;CK syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
+
[https://www.uniprot.org/uniprot/NSDHL_HUMAN NSDHL_HUMAN] CHILD syndrome;CK syndrome. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/NSDHL_HUMAN NSDHL_HUMAN]] Involved in the sequential removal of two C-4 methyl groups in post-squalene cholesterol biosynthesis.<ref>PMID:14506130</ref>
+
[https://www.uniprot.org/uniprot/NSDHL_HUMAN NSDHL_HUMAN] Involved in the sequential removal of two C-4 methyl groups in post-squalene cholesterol biosynthesis.<ref>PMID:14506130</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 25: Line 24:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Kim, D]]
+
[[Category: Kim D]]
-
[[Category: Lee, B]]
+
[[Category: Lee B]]
-
[[Category: Lee, S J]]
+
[[Category: Lee SJ]]
-
[[Category: Cholesterol]]
+
-
[[Category: Dehydrogenase]]
+
-
[[Category: Oxidoreductase]]
+

Current revision

The NAD+-free form of human NSDHL

PDB ID 6jkg

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/6jkg"
Personal tools