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2f12
From Proteopedia
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<StructureSection load='2f12' size='340' side='right'caption='[[2f12]], [[Resolution|resolution]] 2.27Å' scene=''> | <StructureSection load='2f12' size='340' side='right'caption='[[2f12]], [[Resolution|resolution]] 2.27Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2f12]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2f12]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F12 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2F12 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HTM:6-(3-HYDROXYPROPOXY)-5-ACETAMIDO-5,6-DIHYDRO-4-HYDROXY-4H-PYRAN-2-CARBOXYLIC+ACID'>HTM</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2f12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f12 OCA], [https://pdbe.org/2f12 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2f12 RCSB], [https://www.ebi.ac.uk/pdbsum/2f12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2f12 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/NEUR2_HUMAN NEUR2_HUMAN] Hydrolyzes sialylated compounds. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f12 ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2f12 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Neuraminidase 3D structures|Neuraminidase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
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[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Chavas | + | [[Category: Chavas LMG]] |
| - | [[Category: Dyason | + | [[Category: Dyason JC]] |
| - | [[Category: Fusi | + | [[Category: Fusi P]] |
| - | + | [[Category: Kato R]] | |
| - | [[Category: Kato | + | [[Category: Mann MC]] |
| - | [[Category: Mann | + | [[Category: Monti E]] |
| - | [[Category: Monti | + | [[Category: Tettamanti G]] |
| - | [[Category: Tettamanti | + | [[Category: Thomson RJ]] |
| - | [[Category: Thomson | + | [[Category: Tringali C]] |
| - | [[Category: Tringali | + | [[Category: Venerando B]] |
| - | [[Category: Venerando | + | [[Category: Wakatsuki S]] |
| - | [[Category: Wakatsuki | + | [[Category: Von Itzstein M]] |
| - | [[Category: | + | |
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Current revision
Crystal Structure of the Human Sialidase Neu2 in Complex with 3- hydroxypropyl ether mimetic Inhibitor
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Categories: Homo sapiens | Large Structures | Chavas LMG | Dyason JC | Fusi P | Kato R | Mann MC | Monti E | Tettamanti G | Thomson RJ | Tringali C | Venerando B | Wakatsuki S | Von Itzstein M
