6tza

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<StructureSection load='6tza' size='340' side='right'caption='[[6tza]], [[Resolution|resolution]] 7.20&Aring;' scene=''>
<StructureSection load='6tza' size='340' side='right'caption='[[6tza]], [[Resolution|resolution]] 7.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6tza]] is a 14 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TZA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6TZA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6tza]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6TZA FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6tza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tza OCA], [http://pdbe.org/6tza PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tza RCSB], [http://www.ebi.ac.uk/pdbsum/6tza PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tza ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6tza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tza OCA], [https://pdbe.org/6tza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6tza RCSB], [https://www.ebi.ac.uk/pdbsum/6tza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6tza ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IST1_HUMAN IST1_HUMAN]] Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.<ref>PMID:19129479</ref> <ref>PMID:19129480</ref>
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[https://www.uniprot.org/uniprot/IST1_HUMAN IST1_HUMAN] Proposed to be involved in specific functions of the ESCRT machinery. Is required for efficient abscission during cytokinesis, but not for HIV-1 budding. The involvement in the MVB pathway is not established. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells.<ref>PMID:19129479</ref> <ref>PMID:19129480</ref>
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==See Also==
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*[[Increased sodium tolerance protein|Increased sodium tolerance protein]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Frost, A]]
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[[Category: Frost A]]
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[[Category: Nguyen, H C]]
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[[Category: Nguyen HC]]
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[[Category: Escrt-iii]]
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[[Category: Lipid binding protein]]
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[[Category: Membrane remodeling]]
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[[Category: Membrane-bound protein filament]]
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Current revision

CryoEM reconstruction of ESCRT-III filament composed of IST1 NTD R16E K27E double mutant

PDB ID 6tza

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