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6t7y

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Current revision (12:56, 24 January 2024) (edit) (undo)
 
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<StructureSection load='6t7y' size='340' side='right'caption='[[6t7y]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
<StructureSection load='6t7y' size='340' side='right'caption='[[6t7y]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6t7y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"pyrococcus_abyssi"_erauso_et_al._1993 "pyrococcus abyssi" erauso et al. 1993] and [http://en.wikipedia.org/wiki/Pyrab Pyrab]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T7Y OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6T7Y FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6t7y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_abyssi Pyrococcus abyssi] and [https://en.wikipedia.org/wiki/Pyrococcus_abyssi_GE5 Pyrococcus abyssi GE5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6T7Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6T7Y FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pcn, PYRAB13790, PAB1465 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=272844 PYRAB])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6t7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t7y OCA], [https://pdbe.org/6t7y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6t7y RCSB], [https://www.ebi.ac.uk/pdbsum/6t7y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6t7y ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6t7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6t7y OCA], [http://pdbe.org/6t7y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6t7y RCSB], [http://www.ebi.ac.uk/pdbsum/6t7y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6t7y ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PCNA_PYRAB PCNA_PYRAB]] Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (By similarity). Regulates activity of NucS endonuclease and prevents non-specific cleavage.[HAMAP-Rule:MF_00317]<ref>PMID:22431731</ref>
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[https://www.uniprot.org/uniprot/PCNA_PYRAB PCNA_PYRAB] Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (By similarity). Regulates activity of NucS endonuclease and prevents non-specific cleavage.[HAMAP-Rule:MF_00317]<ref>PMID:22431731</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6t7y" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6t7y" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
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*[[Proliferating cell nuclear antigen 3D structures|Proliferating cell nuclear antigen 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Pyrococcus abyssi erauso et al. 1993]]
 
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[[Category: DNA-directed DNA polymerase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pyrab]]
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[[Category: Pyrococcus abyssi]]
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[[Category: Beaufet, I Hugonneau]]
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[[Category: Pyrococcus abyssi GE5]]
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[[Category: Carroni, M]]
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[[Category: Carroni M]]
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[[Category: Delarue, M]]
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[[Category: Delarue M]]
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[[Category: Madru, C]]
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[[Category: Hugonneau Beaufet I]]
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[[Category: Raia, P]]
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[[Category: Madru C]]
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[[Category: Sauguet, L]]
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[[Category: Raia P]]
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[[Category: Dp2]]
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[[Category: Sauguet L]]
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[[Category: Pcna]]
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[[Category: Pip-box]]
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[[Category: Pold]]
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[[Category: Replication]]
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Current revision

Structure of PCNA bound to cPIP motif of DP2 from P. abyssi

PDB ID 6t7y

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