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5de3
From Proteopedia
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<StructureSection load='5de3' size='340' side='right'caption='[[5de3]], [[Resolution|resolution]] 1.42Å' scene=''> | <StructureSection load='5de3' size='340' side='right'caption='[[5de3]], [[Resolution|resolution]] 1.42Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5de3]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5de3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DE3 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.417Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5de3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5de3 OCA], [https://pdbe.org/5de3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5de3 RCSB], [https://www.ebi.ac.uk/pdbsum/5de3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5de3 ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/ARL3_CHLRE ARL3_CHLRE] Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Required for targeting proteins to the ciliary membrane by releasing myristoylated protein from unc119 cargo adapters into the cilium.[UniProtKB:P36405] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Chlamydomonas reinhardtii]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Gotthardt | + | [[Category: Gotthardt K]] |
| - | [[Category: Lokaj | + | [[Category: Lokaj M]] |
| - | [[Category: Wittinghofer | + | [[Category: Wittinghofer A]] |
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Current revision
The Crystal structure of Chlamydomonas reinhardtii Arl3 bound to GppNHp
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