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5m6s
From Proteopedia
(Difference between revisions)
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<SX load='5m6s' size='340' side='right' viewer='molstar' caption='[[5m6s]], [[Resolution|resolution]] 4.80Å' scene=''> | <SX load='5m6s' size='340' side='right' viewer='molstar' caption='[[5m6s]], [[Resolution|resolution]] 4.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5m6s]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5m6s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5M6S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5M6S FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.8Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5m6s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5m6s OCA], [https://pdbe.org/5m6s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5m6s RCSB], [https://www.ebi.ac.uk/pdbsum/5m6s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5m6s ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LPTN_ECOLI LPTN_ECOLI] Required for tryptophan-regulated expression of the tna operon. In the presence of free L-Trp release of this nascent peptide by release factor 2 is inhibited and the ribosome stalls with the last amino acid in the P site and a UGA stop codon in the A site. This prevent transcripiton termination factor Rho binding, and thus allows transcription and translation of TnaA and TnaB.[https://www.uniprot.org/uniprot/SPTN1_CHICK SPTN1_CHICK] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization. | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
| - | *[[Spectrin|Spectrin]] | + | *[[Spectrin 3D structures|Spectrin 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</SX> | </SX> | ||
| - | [[Category: | + | [[Category: Escherichia coli]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Clarke | + | [[Category: Clarke J]] |
| - | [[Category: Nickson | + | [[Category: Nickson AA]] |
| - | [[Category: Nilsson | + | [[Category: Nilsson OB]] |
| - | + | ||
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Current revision
folding intermediate of spectrin R16
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