5tfy

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Current revision (15:40, 6 March 2024) (edit) (undo)
 
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<SX load='5tfy' size='340' side='right' viewer='molstar' caption='[[5tfy]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
<SX load='5tfy' size='340' side='right' viewer='molstar' caption='[[5tfy]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5tfy]] is a 26 chain structure with sequence from [http://en.wikipedia.org/wiki/Methj Methj]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TFY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5TFY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5tfy]] is a 26 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanospirillum_hungatei_JF-1 Methanospirillum hungatei JF-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TFY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TFY FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5tfy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tfy OCA], [http://pdbe.org/5tfy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tfy RCSB], [http://www.ebi.ac.uk/pdbsum/5tfy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tfy ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tfy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tfy OCA], [https://pdbe.org/5tfy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tfy RCSB], [https://www.ebi.ac.uk/pdbsum/5tfy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tfy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/Q2FUM4_METHJ Q2FUM4_METHJ]] Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.[RuleBase:RU361282]
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[https://www.uniprot.org/uniprot/Q2FUM4_METHJ Q2FUM4_METHJ] Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella.[RuleBase:RU361282]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Archaea use flagella known as archaella-distinct both in protein composition and structure from bacterial flagella-to drive cell motility, but the structural basis of this function is unknown. Here, we report an atomic model of the archaella, based on the cryo electron microscopy (cryoEM) structure of the Methanospirillum hungatei archaellum at 3.4 A resolution. Each archaellum contains approximately 61,500 archaellin subunits organized into a curved helix with a diameter of 10 nm and average length of 10,000 nm. The tadpole-shaped archaellin monomer has two domains, a beta-barrel domain and a long, mildly kinked alpha-helix tail. Our structure reveals multiple post-translational modifications to the archaella, including six O-linked glycans and an unusual N-linked modification. The extensive interactions among neighbouring archaellins explain how the long but thin archaellum maintains the structural integrity required for motility-driving rotation. These extensive inter-subunit interactions and the absence of a central pore in the archaellum distinguish it from both the bacterial flagellum and type IV pili.
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CryoEM structure of the Methanospirillum hungatei archaellum reveals structural features distinct from the bacterial flagellum and type IV pili.,Poweleit N, Ge P, Nguyen HH, Loo RR, Gunsalus RP, Zhou ZH Nat Microbiol. 2016 Dec 5;2:16222. doi: 10.1038/nmicrobiol.2016.222. PMID:27922015<ref>PMID:27922015</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 5tfy" style="background-color:#fffaf0;"></div>
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==See Also==
==See Also==
*[[Flagellin 3D structures|Flagellin 3D structures]]
*[[Flagellin 3D structures|Flagellin 3D structures]]
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== References ==
 
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<references/>
 
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Methj]]
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[[Category: Methanospirillum hungatei JF-1]]
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[[Category: Gunsalus, R P]]
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[[Category: Gunsalus RP]]
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[[Category: Peng, G]]
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[[Category: Peng G]]
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[[Category: Poweleit, N]]
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[[Category: Poweleit N]]
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[[Category: Zhou, Z H]]
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[[Category: Zhou ZH]]
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[[Category: Cell adhesion]]
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[[Category: Cell motility and adhesion]]
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Current revision

The archaeal flagellum of Methanospirillum hungatei strain JF1.

5tfy, resolution 3.40Å

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