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6v11

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<SX load='6v11' size='340' side='right' viewer='molstar' caption='[[6v11]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
<SX load='6v11' size='340' side='right' viewer='molstar' caption='[[6v11]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6v11]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_pestis"_(lehmann_and_neumann_1896)_migula_1900 "bacillus pestis" (lehmann and neumann 1896) migula 1900]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V11 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=6V11 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6v11]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_pestis Yersinia pestis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6V11 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6V11 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6on2|6on2]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lon, YP_0776, EGT45_05820, NCTC144_01047 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=632 "Bacillus pestis" (Lehmann and Neumann 1896) Migula 1900])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6v11 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v11 OCA], [https://pdbe.org/6v11 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6v11 RCSB], [https://www.ebi.ac.uk/pdbsum/6v11 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6v11 ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endopeptidase_La Endopeptidase La], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.53 3.4.21.53] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=6v11 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6v11 OCA], [http://pdbe.org/6v11 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6v11 RCSB], [http://www.ebi.ac.uk/pdbsum/6v11 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6v11 ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A5P8YJ65_YERPE A0A5P8YJ65_YERPE] ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.[HAMAP-Rule:MF_01973]
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__TOC__
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</SX>
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[[Category: Endopeptidase La]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Adjei, E]]
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[[Category: Yersinia pestis]]
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[[Category: Asmita, A]]
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[[Category: Adjei E]]
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[[Category: Karzai, A W]]
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[[Category: Asmita A]]
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[[Category: Lander, G C]]
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[[Category: Karzai AW]]
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[[Category: Puchades, C]]
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[[Category: Lander GC]]
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[[Category: Puri, N]]
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[[Category: Puchades C]]
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[[Category: Shin, M]]
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[[Category: Puri N]]
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[[Category: Wiseman, R L]]
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[[Category: Shin M]]
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[[Category: Aaa+ atpase]]
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[[Category: Wiseman RL]]
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[[Category: Hydrolase]]
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[[Category: Protease]]
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[[Category: Quality control]]
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Current revision

Lon Protease from Yersinia pestis

6v11, resolution 3.80Å

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