This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6wfn
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6wfn is ON HOLD Authors: Greasley, S.E., Feng, J., Deng, Y.-L., Stewart, A.E. Description: Crystal structure of human Naa50 in complex with AcCoA a...) |
|||
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human Naa50 in complex with AcCoA and an inhibitor (compound 4a) identified using DNA encoded library technology== | |
| - | + | <StructureSection load='6wfn' size='340' side='right'caption='[[6wfn]], [[Resolution|resolution]] 1.07Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6wfn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WFN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WFN FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.07Å</td></tr> | |
| - | [[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=U2J:(4S)-1-methyl-N-{(3S,5S)-5-[4-(methylcarbamoyl)-1,3-thiazol-2-yl]-1-[4-(1H-tetrazol-5-yl)benzene-1-carbonyl]pyrrolidin-3-yl}-2,6-dioxohexahydropyrimidine-4-carboxamide'>U2J</scene></td></tr> |
| - | [[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wfn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wfn OCA], [https://pdbe.org/6wfn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wfn RCSB], [https://www.ebi.ac.uk/pdbsum/6wfn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wfn ProSAT]</span></td></tr> |
| - | [[ | + | </table> |
| - | [[Category: Deng | + | == Function == |
| - | [[Category: Stewart | + | [https://www.uniprot.org/uniprot/NAA50_HUMAN NAA50_HUMAN] Probable catalytic component of the NAA11-NAA15 complex which displays alpha (N-terminal) acetyltransferase activity.<ref>PMID:16507339</ref> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Deng Y-L]] | ||
| + | [[Category: Feng J]] | ||
| + | [[Category: Greasley SE]] | ||
| + | [[Category: Stewart AE]] | ||
Current revision
Crystal structure of human Naa50 in complex with AcCoA and an inhibitor (compound 4a) identified using DNA encoded library technology
| |||||||||||
