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6wfv
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6wfv is ON HOLD until Paper Publication Authors: Guo, H., Miller, M.D. Description: The crystal structure of a collagen galactosylhydroxylysyl gluc...) |
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| - | '''Unreleased structure''' | ||
| - | The | + | ==The crystal structure of a collagen galactosylhydroxylysyl glucosyltransferase from human== |
| - | + | <StructureSection load='6wfv' size='340' side='right'caption='[[6wfv]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[6wfv]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WFV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wfv OCA], [https://pdbe.org/6wfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wfv RCSB], [https://www.ebi.ac.uk/pdbsum/6wfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wfv ProSAT]</span></td></tr> |
| - | [[Category: Guo | + | </table> |
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/PLOD3_HUMAN PLOD3_HUMAN] Connective tissue disorder due to lysyl hydroxylase-3 deficiency. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PLOD3_HUMAN PLOD3_HUMAN] Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links.[UniProtKB:P24802] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Guo H-F]] | ||
| + | [[Category: Kurie JM]] | ||
| + | [[Category: Miller MD]] | ||
| + | [[Category: Phillips Jr GN]] | ||
| + | [[Category: Tainer JA]] | ||
| + | [[Category: Tsai C-L]] | ||
Current revision
The crystal structure of a collagen galactosylhydroxylysyl glucosyltransferase from human
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